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Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications.

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Title: Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications.
Authors: Yang Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China., He Y; The First Department of Medical Oncology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China., Zhang Z; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Zhang Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Gao R; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Du K; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Wu Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China., Wu J; Shenyang Key Laboratory of Chronic Disease Assessment and Nutritional Intervention for Heart and Brain, Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn.; The Second Affiliated Hospital of Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn., Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. minjie_wei@163.com.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China. minjie_wei@163.com.; Liaoning Medical Diagnosis and Treatment Center, Shenyang, China. minjie_wei@163.com., Liu M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. saffer@163.com.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jul 06; Vol. 11 (1). Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; The First Department of Medical Oncology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Gao+R%22">Gao R</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Du+K%22">Du K</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Shenyang Key Laboratory of Chronic Disease Assessment and Nutritional Intervention for Heart and Brain, Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn.; The Second Affiliated Hospital of Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wei+M%22">Wei M</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. minjie_wei@163.com.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China. minjie_wei@163.com.; Liaoning Medical Diagnosis and Treatment Center, Shenyang, China. minjie_wei@163.com.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. saffer@163.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41392-026-02757-7
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        Text: English
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              Text: 2026 Jul 06
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