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Fus-depleted oligodendrocytes reduce neuronal damage and Alzheimer's disease progression in the AppNL-G-F mouse.

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Title: Fus-depleted oligodendrocytes reduce neuronal damage and Alzheimer's disease progression in the AppNL-G-F mouse.
Authors: Tung TH; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Babu S; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Tang X; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Sciutto AL; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Romer M; Children Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA., Racha P; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Xu R; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA,15213  USA., Fiesler V; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Saha A; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Thai T; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Saito T; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University, Nagoya, Aichi, 467-8601, Japan.; Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan., Saido TC; RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan., Zhao Y; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA,15213  USA.; Carnegie Mellon Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Grinspan JB; Children Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA., Mathys H; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA., Kozai TDY; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, 15213, USA.; Carnegie Mellon Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA., Cambi F; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; VA Pittsburgh Healthcare System, Pittsburgh, PA, 15240, USA.
Source: Brain : a journal of neurology [Brain] 2026 Jul 06. Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Fus-depleted oligodendrocytes reduce neuronal damage and Alzheimer's disease progression in the AppNL-G-F mouse.
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  Data: <searchLink fieldCode="AU" term="%22Tung+TH%22">Tung TH</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Babu+S%22">Babu S</searchLink>; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Sciutto+AL%22">Sciutto AL</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Romer+M%22">Romer M</searchLink>; Children Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Racha+P%22">Racha P</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Xu+R%22">Xu R</searchLink>; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA,15213  USA.<br /><searchLink fieldCode="AU" term="%22Fiesler+V%22">Fiesler V</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Saha+A%22">Saha A</searchLink>; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Thai+T%22">Thai T</searchLink>; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Saito+T%22">Saito T</searchLink>; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University, Nagoya, Aichi, 467-8601, Japan.; Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.<br /><searchLink fieldCode="AU" term="%22Saido+TC%22">Saido TC</searchLink>; RIKEN Brain Science Institute, Wako, Saitama, 351-0198, Japan.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA,15213  USA.; Carnegie Mellon Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.<br /><searchLink fieldCode="AU" term="%22Grinspan+JB%22">Grinspan JB</searchLink>; Children Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Mathys+H%22">Mathys H</searchLink>; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.<br /><searchLink fieldCode="AU" term="%22Kozai+TDY%22">Kozai TDY</searchLink>; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, 15213, USA.; Carnegie Mellon Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.<br /><searchLink fieldCode="AU" term="%22Cambi+F%22">Cambi F</searchLink>; Pittsburgh Institute for Neurodegenerative Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.; VA Pittsburgh Healthcare System, Pittsburgh, PA, 15240, USA.
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        Value: 10.1093/brain/awag234
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        Text: English
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      – TitleFull: Fus-depleted oligodendrocytes reduce neuronal damage and Alzheimer's disease progression in the AppNL-G-F mouse.
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              Text: 2026 Jul 06
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