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Neonatal CD19+B220lo cells sense microbiota via TLR2/4 activation driving proliferation and differentiation.

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Title: Neonatal CD19+B220lo cells sense microbiota via TLR2/4 activation driving proliferation and differentiation.
Authors: Ruiz-Sánchez C; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Cortegano I; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Rodríguez M; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Sanchez-Tarjuelo R; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Arrabal A; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Prado MC; Flow Cytometry Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain., Alia M; Flow Cytometry Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain., Jiménez MP; Genomic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain., Lopez Molina VM; Bioinformatic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain., Monzón S; Bioinformatic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain., López-Alonso V; Computational Biology Unit, Chronic Disease Research Program, ISCIII, Majadahonda, Spain., de Andrés B; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain., Gaspar ML; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 19; Vol. 17, pp. 1838044. Date of Electronic Publication: 2026 Jun 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neonatal CD19<superscript>+</superscript>B220<superscript>lo</superscript> cells sense microbiota via TLR2/4 activation driving proliferation and differentiation.
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  Data: <searchLink fieldCode="AU" term="%22Ruiz-Sánchez+C%22">Ruiz-Sánchez C</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Cortegano+I%22">Cortegano I</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+M%22">Rodríguez M</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Tarjuelo+R%22">Sanchez-Tarjuelo R</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Arrabal+A%22">Arrabal A</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Prado+MC%22">Prado MC</searchLink>; Flow Cytometry Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Alia+M%22">Alia M</searchLink>; Flow Cytometry Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Jiménez+MP%22">Jiménez MP</searchLink>; Genomic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Lopez+Molina+VM%22">Lopez Molina VM</searchLink>; Bioinformatic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Monzón+S%22">Monzón S</searchLink>; Bioinformatic Unit, Central Core Laboratories, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22López-Alonso+V%22">López-Alonso V</searchLink>; Computational Biology Unit, Chronic Disease Research Program, ISCIII, Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22de+Andrés+B%22">de Andrés B</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.<br /><searchLink fieldCode="AU" term="%22Gaspar+ML%22">Gaspar ML</searchLink>; Immunobiology Unit, Immunology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Majadahonda, Spain.
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