REJENERA©, a multi-component bioflavonoid-based formula, alleviates osteoarthritis and provides chondroprotection by regulating the NLRP3-TXNIP-iNOS axis and inflammation: a comparative study with olive leaf nutraceuticals and ibuprofen.
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| Title: | REJENERA©, a multi-component bioflavonoid-based formula, alleviates osteoarthritis and provides chondroprotection by regulating the NLRP3-TXNIP-iNOS axis and inflammation: a comparative study with olive leaf nutraceuticals and ibuprofen. |
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| Authors: | Tepedelenlioglu HE; Department of Orthopedics and Traumatology, Ankara Dışkapı Training and Research Hospital, Ankara, Turkey.; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Ankara, Turkey., Elmazoglu Z; Department of Pharmacology, Faculty of Pharmacy, Ankara Medipol University, Ankara, Turkey., Saribas SG; Department of Histology and Embryology, Faculty of Medicine, Health Sciences University Gulhane, Ankara, Turkey., Tutuncu Y; Department of Immunology, School of Medicine, Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.; Department of Medical Microbiology, Inonu University Faculty of Medicine, Malatya, Turkey., Ceylan AF; Department of Medical Pharmacology, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Turkey., Karasu Ç; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Ankara, Turkey. karasu@gazi.edu.tr. |
| Source: | Inflammopharmacology [Inflammopharmacology] 2026 Jul 06. Date of Electronic Publication: 2026 Jul 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42406250 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: REJENERA<superscript>©</superscript>, a multi-component bioflavonoid-based formula, alleviates osteoarthritis and provides chondroprotection by regulating the NLRP3-TXNIP-iNOS axis and inflammation: a comparative study with olive leaf nutraceuticals and ibuprofen. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tepedelenlioglu+HE%22">Tepedelenlioglu HE</searchLink>; Department of Orthopedics and Traumatology, Ankara Dışkapı Training and Research Hospital, Ankara, Turkey.; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Elmazoglu+Z%22">Elmazoglu Z</searchLink>; Department of Pharmacology, Faculty of Pharmacy, Ankara Medipol University, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Saribas+SG%22">Saribas SG</searchLink>; Department of Histology and Embryology, Faculty of Medicine, Health Sciences University Gulhane, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Tutuncu+Y%22">Tutuncu Y</searchLink>; Department of Immunology, School of Medicine, Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.; Department of Medical Microbiology, Inonu University Faculty of Medicine, Malatya, Turkey.<br /><searchLink fieldCode="AU" term="%22Ceylan+AF%22">Ceylan AF</searchLink>; Department of Medical Pharmacology, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Karasu+Ç%22">Karasu Ç</searchLink>; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Ankara, Turkey. karasu@gazi.edu.tr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229112626%22">Inflammopharmacology</searchLink> [Inflammopharmacology] 2026 Jul 06. <i>Date of Electronic Publication: </i>2026 Jul 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Birkhäuser%22">Birkhäuser </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9112626 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1568-5608 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209254692%22">09254692 </searchLink><i>NLM ISO Abbreviation: </i>Inflammopharmacology <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42406250 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10787-026-02314-2 Languages: – Code: eng Text: English Titles: – TitleFull: REJENERA©, a multi-component bioflavonoid-based formula, alleviates osteoarthritis and provides chondroprotection by regulating the NLRP3-TXNIP-iNOS axis and inflammation: a comparative study with olive leaf nutraceuticals and ibuprofen. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tepedelenlioglu HE – PersonEntity: Name: NameFull: Elmazoglu Z – PersonEntity: Name: NameFull: Saribas SG – PersonEntity: Name: NameFull: Tutuncu Y – PersonEntity: Name: NameFull: Ceylan AF – PersonEntity: Name: NameFull: Karasu Ç IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 07 Text: 2026 Jul 06 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1568-5608 Titles: – TitleFull: Inflammopharmacology Type: main |
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