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Aerobic Exercise and Subthreshold Depressive Symptoms in Adolescents: Secondary Analysis of a Randomized Clinical Trial.

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Title: Aerobic Exercise and Subthreshold Depressive Symptoms in Adolescents: Secondary Analysis of a Randomized Clinical Trial.
Authors: Yan X; Department of Medical Imaging, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, P.R. China.; School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, P.R. China., Shao R; Department of Psychology, The University of Hong Kong, Hong Kong SAR, P.R. China., Jin J; Department of Psychology, The University of Hong Kong, Hong Kong SAR, P.R. China., Lu W; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, P.R. China.; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China., Jiang Z; College of Psychology, Liaoning Normal University, Dalian, Liaoning, P.R. China., Zhang G; Institute of Psychological and Brain Sciences, Liaoning Normal University, Dalian, Liaoning, P.R. China.; Key Laboratory of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, Liaoning, P.R. China., Zhang Q; Department of Medical Imaging, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, P.R. China., Li X; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China., Tian X; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China., Stubbs B; Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, United Kingdom., Vancampfort D; University Psychiatric Centre KU Leuven, Leuven, Belgium.; Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium., Solmi M; Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.; Regional Centre for the Treatment of Eating Disorders and On Track: Champlain First Episode Psychosis Program, Department of Mental Health, The Ottawa Hospital, Ottawa, Ontario, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, University of Ottawa, Ottawa, Canada.; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany., Fornaro M; Department of Psychiatry, Federico II University of Naples, Naples, Italy., Carvalho AF; Institute for Mental and Physical Health and Clinical Translation (IMPACT) Strategic Research Centre, Deakin Medical School, Barwon Health, Deakin University, Geelong, Victoria, Australia., Yau SS; Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, P.R. China.; University Research Facility in Behavioral and Systems Neuroscience, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, P.R. China., Cong F; School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, P.R. China.; Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland., So KF; Ministry of Education Joint International Research Laboratory of CNS Regeneration, Jinan University, Guangzhou, Guangdong Province, P.R. China., Lin K; Department of Psychiatry and Behavioral Sciences, School of Medicine, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong, P.R. China.
Source: JAMA network open [JAMA Netw Open] 2026 Jul 01; Vol. 9 (7), pp. e2621568. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Department of Medical Imaging, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, P.R. China.; School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, P.R. China.<br /><searchLink fieldCode="AU" term="%22Shao+R%22">Shao R</searchLink>; Department of Psychology, The University of Hong Kong, Hong Kong SAR, P.R. China.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; Department of Psychology, The University of Hong Kong, Hong Kong SAR, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lu+W%22">Lu W</searchLink>; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, P.R. China.; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China.<br /><searchLink fieldCode="AU" term="%22Jiang+Z%22">Jiang Z</searchLink>; College of Psychology, Liaoning Normal University, Dalian, Liaoning, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Institute of Psychological and Brain Sciences, Liaoning Normal University, Dalian, Liaoning, P.R. China.; Key Laboratory of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, Liaoning, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Department of Medical Imaging, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, P.R. China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China.<br /><searchLink fieldCode="AU" term="%22Tian+X%22">Tian X</searchLink>; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, P.R. China.<br /><searchLink fieldCode="AU" term="%22Stubbs+B%22">Stubbs B</searchLink>; Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vancampfort+D%22">Vancampfort D</searchLink>; University Psychiatric Centre KU Leuven, Leuven, Belgium.; Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Solmi+M%22">Solmi M</searchLink>; Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.; Regional Centre for the Treatment of Eating Disorders and On Track: Champlain First Episode Psychosis Program, Department of Mental Health, The Ottawa Hospital, Ottawa, Ontario, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, University of Ottawa, Ottawa, Canada.; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Fornaro+M%22">Fornaro M</searchLink>; Department of Psychiatry, Federico II University of Naples, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Carvalho+AF%22">Carvalho AF</searchLink>; Institute for Mental and Physical Health and Clinical Translation (IMPACT) Strategic Research Centre, Deakin Medical School, Barwon Health, Deakin University, Geelong, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Yau+SS%22">Yau SS</searchLink>; Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, P.R. China.; University Research Facility in Behavioral and Systems Neuroscience, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, P.R. China.<br /><searchLink fieldCode="AU" term="%22Cong+F%22">Cong F</searchLink>; School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, P.R. China.; Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22So+KF%22">So KF</searchLink>; Ministry of Education Joint International Research Laboratory of CNS Regeneration, Jinan University, Guangzhou, Guangdong Province, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lin+K%22">Lin K</searchLink>; Department of Psychiatry and Behavioral Sciences, School of Medicine, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2026 Jul 01; Vol. 9 (7), pp. e2621568. <i>Date of Electronic Publication: </i>2026 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101729235 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2574-3805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225743805%22">25743805 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Netw Open <i>Subsets: </i>MEDLINE
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