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Long-term stability and performance of Cas9/guide RNA-based gene drives in anopheline mosquitoes.

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Title: Long-term stability and performance of Cas9/guide RNA-based gene drives in anopheline mosquitoes.
Authors: Carballar-Lejarazú R; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Dong Y; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205., Pham TB; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Tushar T; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Stillinger D; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Nguyen DN; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Winokur L; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025., Tavadia M; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205., Tao M; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205., Dimopoulos G; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205., James AA; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jul 14; Vol. 123 (28), pp. e2605739123. Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Long-term stability and performance of Cas9/guide RNA-based gene drives in anopheline mosquitoes.
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  Data: <searchLink fieldCode="AU" term="%22Carballar-Lejarazú+R%22">Carballar-Lejarazú R</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Dong+Y%22">Dong Y</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.<br /><searchLink fieldCode="AU" term="%22Pham+TB%22">Pham TB</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Tushar+T%22">Tushar T</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Stillinger+D%22">Stillinger D</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Nguyen+DN%22">Nguyen DN</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Winokur+L%22">Winokur L</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.<br /><searchLink fieldCode="AU" term="%22Tavadia+M%22">Tavadia M</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.<br /><searchLink fieldCode="AU" term="%22Tao+M%22">Tao M</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.<br /><searchLink fieldCode="AU" term="%22Dimopoulos+G%22">Dimopoulos G</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Malaria Research Institute, Johns Hopkins University, Baltimore, MD 21205.<br /><searchLink fieldCode="AU" term="%22James+AA%22">James AA</searchLink>; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697-4025.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Jul 14; Vol. 123 (28), pp. e2605739123. <i>Date of Electronic Publication: </i>2026 Jul 06.
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              Text: 2026 Jul 14
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