Defining neonatal encephalopathy: an international real-time Delphi consensus process.

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Title: Defining neonatal encephalopathy: an international real-time Delphi consensus process.
Authors: Branagan A; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland., Hurley T; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland., Byrne D; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland., Quirke F; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Medicine, University of Limerick, Limerick, Ireland., Devane D; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Nursing and Midwifery, University of Galway, Galway, Ireland; Evidence Synthesis Ireland, University of Galway, Galway, Ireland; Cochrane Ireland, University of Galway, Galway, Ireland., Taneri PE; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Nursing and Midwifery, University of Galway, Galway, Ireland., Badawi N; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia; Grace Centre for Newborn Intensive Care, Sydney Children's Hospital Network, The University of Sydney, Westmead, NSW, Australia., Bearer CF; Division of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Bloomfield FH; Liggins Institute, University of Auckland, Auckland, New Zealand., Bonifacio SL; Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA., Boylan G; INFANT Research Centre, Cork, Ireland; Department of Pediatrics and Child Health, University College Cork, Cork, Ireland., Campbell SK; Department of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, USA., Chalak L; Division of Neonatal-Perinatal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., D'Alton M; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA., de Vries LS; Department of Neonatology, Willem-Alexander Children's Hospital Leiden University Medical Center, Leiden, Netherlands., El-Dib M; Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children Harvard Medical School, Boston, MA, USA., Ferriero DM; Departments of Neurology and Pediatrics, Weill Institute for Neurosciences, University of California San Francisco, CA, USA., Gale C; Neonatal Medicine, School of Public Health, and Centre for Paediatrics and Child Health, Faculty of Medicine, Imperial College London, London, UK., Gressens P; Université Paris Cité, INSERM, NeuroDiderot, Paris, France., Gronlund T; James Lind Alliance, School of Healthcare Enterprise and Innovation, University of Southampton, Southampton, UK., Gunn AJ; Departments of Physiology and Paediatrics, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Kay S; PEEPS-HIE, Manchester, UK., Murray DM; INFANT Research Centre, Cork, Ireland; Department of Pediatrics and Child Health, University College Cork, Cork, Ireland., Nelson KB; National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA., Pilon B; Hope for HIE, West Bloomfield, MI, USA., Robertson NJ; Institute for Women's Health, University College London, London, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Walker K; Department of Newborn Care, Royal Prince Alfred Hospital, Sydney, Local Health District, Sydney, NSW, Australia; Reproductive and Perinatal Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia., Wusthoff CJ; Department of Neurology, University of California-Davis Health, Sacramento, CA, USA., Molloy EJ; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland; Neonatology, Children's Health Ireland, Dublin, Ireland; Neurodisability, Children's Hospital Ireland at Tallaght, Dublin, Ireland. Electronic address: eleanor.molloy@tcd.ie.
Corporate Authors: Steering Group for DEFiNE (Definition of Neonatal Encephalopathy)
Source: The Lancet. Child & adolescent health [Lancet Child Adolesc Health] 2026 Sep; Vol. 10 (9), pp. 679-686. Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article; Consensus Statement; Systematic Review; Review
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101712925 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-4650 (Electronic) Linking ISSN: 23524642 NLM ISO Abbreviation: Lancet Child Adolesc Health Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Branagan+A%22">Branagan A</searchLink>; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Hurley+T%22">Hurley T</searchLink>; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Byrne+D%22">Byrne D</searchLink>; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Quirke+F%22">Quirke F</searchLink>; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Medicine, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Devane+D%22">Devane D</searchLink>; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Nursing and Midwifery, University of Galway, Galway, Ireland; Evidence Synthesis Ireland, University of Galway, Galway, Ireland; Cochrane Ireland, University of Galway, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Taneri+PE%22">Taneri PE</searchLink>; Health Research Board-Trials Methodology, Research Network, University of Galway, Galway, Ireland; School of Nursing and Midwifery, University of Galway, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Badawi+N%22">Badawi N</searchLink>; Cerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Sydney Medical School, Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia; Grace Centre for Newborn Intensive Care, Sydney Children's Hospital Network, The University of Sydney, Westmead, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Bearer+CF%22">Bearer CF</searchLink>; Division of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Bloomfield+FH%22">Bloomfield FH</searchLink>; Liggins Institute, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Bonifacio+SL%22">Bonifacio SL</searchLink>; Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Boylan+G%22">Boylan G</searchLink>; INFANT Research Centre, Cork, Ireland; Department of Pediatrics and Child Health, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Campbell+SK%22">Campbell SK</searchLink>; Department of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Chalak+L%22">Chalak L</searchLink>; Division of Neonatal-Perinatal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22D'Alton+M%22">D'Alton M</searchLink>; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22de+Vries+LS%22">de Vries LS</searchLink>; Department of Neonatology, Willem-Alexander Children's Hospital Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22El-Dib+M%22">El-Dib M</searchLink>; Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ferriero+DM%22">Ferriero DM</searchLink>; Departments of Neurology and Pediatrics, Weill Institute for Neurosciences, University of California San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gale+C%22">Gale C</searchLink>; Neonatal Medicine, School of Public Health, and Centre for Paediatrics and Child Health, Faculty of Medicine, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gressens+P%22">Gressens P</searchLink>; Université Paris Cité, INSERM, NeuroDiderot, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gronlund+T%22">Gronlund T</searchLink>; James Lind Alliance, School of Healthcare Enterprise and Innovation, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Gunn+AJ%22">Gunn AJ</searchLink>; Departments of Physiology and Paediatrics, School of Medical Sciences, University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Kay+S%22">Kay S</searchLink>; PEEPS-HIE, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Murray+DM%22">Murray DM</searchLink>; INFANT Research Centre, Cork, Ireland; Department of Pediatrics and Child Health, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Nelson+KB%22">Nelson KB</searchLink>; National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pilon+B%22">Pilon B</searchLink>; Hope for HIE, West Bloomfield, MI, USA.<br /><searchLink fieldCode="AU" term="%22Robertson+NJ%22">Robertson NJ</searchLink>; Institute for Women's Health, University College London, London, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Walker+K%22">Walker K</searchLink>; Department of Newborn Care, Royal Prince Alfred Hospital, Sydney, Local Health District, Sydney, NSW, Australia; Reproductive and Perinatal Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Wusthoff+CJ%22">Wusthoff CJ</searchLink>; Department of Neurology, University of California-Davis Health, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Molloy+EJ%22">Molloy EJ</searchLink>; Discipline of Paediatrics, Trinity College Dublin, the University of Dublin, Dublin, Ireland; Trinity Translational Medicine Institute, St James Hospital & Trinity Research in Childhood Centre, Dublin, Ireland; Neonatology, The Coombe Hospital, Dublin, Ireland; Health Research Board Neonatal Encephalopathy PhD Training Network (NEPTuNE), Dublin, Ireland; Neonatology, Children's Health Ireland, Dublin, Ireland; Neurodisability, Children's Hospital Ireland at Tallaght, Dublin, Ireland. Electronic address: eleanor.molloy@tcd.ie.
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  Data: <searchLink fieldCode="JN" term="%22101712925%22">The Lancet. Child & adolescent health</searchLink> [Lancet Child Adolesc Health] 2026 Sep; Vol. 10 (9), pp. 679-686. <i>Date of Electronic Publication: </i>2026 Jul 06.
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