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Maternal immune activation induces sex-dependent metabolic, epigenetic and GABAergic trajectories in the hippocampus.

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Title: Maternal immune activation induces sex-dependent metabolic, epigenetic and GABAergic trajectories in the hippocampus.
Authors: McEwan F; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom. Electronic address: Francesca.mcewan@manchester.ac.uk., Santo JD; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom., Kambara C; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom., Tarrat-Castells M; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom; Faculty of Medicine and Life Sciences, Universidad Pompeu Fabra, Barcelona 08002, Spain., Woods RM; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom., Harte M; Division of Pharmacy & Optometry, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M13 9PL, United Kingdom., Glazier JD; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom., Hager R; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Jul 06; Vol. 138, pp. 106895. Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22McEwan+F%22">McEwan F</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom. Electronic address: Francesca.mcewan@manchester.ac.uk.<br /><searchLink fieldCode="AU" term="%22Santo+JD%22">Santo JD</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kambara+C%22">Kambara C</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tarrat-Castells+M%22">Tarrat-Castells M</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom; Faculty of Medicine and Life Sciences, Universidad Pompeu Fabra, Barcelona 08002, Spain.<br /><searchLink fieldCode="AU" term="%22Woods+RM%22">Woods RM</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harte+M%22">Harte M</searchLink>; Division of Pharmacy & Optometry, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M13 9PL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Glazier+JD%22">Glazier JD</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hager+R%22">Hager R</searchLink>; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Lydia Becker Institute of Immunology and Inflammation, Geoffrey Jefferson Centre for Brain Research, Faculty of Biology, Medicine & Health, University of Manchester, Manchester M13 9PL, United Kingdom.
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              Text: 2026 Jul 06
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