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SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.

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Title: SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.
Authors: Altulea A; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands., Mackedenski S; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands., Nehme J; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands., Demaria M; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands. m.demaria@umcg.nl.
Source: The EMBO journal [EMBO J] 2026 Jul 06. Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Altulea+A%22">Altulea A</searchLink>; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mackedenski+S%22">Mackedenski S</searchLink>; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nehme+J%22">Nehme J</searchLink>; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Demaria+M%22">Demaria M</searchLink>; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen (RUG), Groningen, The Netherlands. m.demaria@umcg.nl.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8208664 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2075 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202614189%22">02614189 </searchLink><i>NLM ISO Abbreviation: </i>EMBO J <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s44318-026-00845-6
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      – TitleFull: SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.
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              Text: 2026 Jul 06
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