An Integrated Approach Reveals the Pre-Osteoblast-Driven Metrnl Synergizes With Circadian Genes to Inhibit Osteogenesis.

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Title: An Integrated Approach Reveals the Pre-Osteoblast-Driven Metrnl Synergizes With Circadian Genes to Inhibit Osteogenesis.
Authors: Fei W; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Xu K; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Xu M; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Liu T; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Han X; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Zhou C; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Tong W; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Yue Z; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Li Y; Central Laboratory, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China., Hong Y; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.; Shanghai Clinical Research Center for Aging and Medicine, 200040 Shanghai, China.; Center of Community-Based Health Research, Fudan University, 200040 Shanghai, China.
Source: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2026 Jun 24; Vol. 31 (6), pp. 53692.
Publication Type: Journal Article
Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Fei+W%22">Fei W</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+M%22">Xu M</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+C%22">Zhou C</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Tong+W%22">Tong W</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yue+Z%22">Yue Z</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Central Laboratory, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hong+Y%22">Hong Y</searchLink>; Department of Orthopedics, The Fifth People's Hospital of Shanghai, Fudan University, 200040 Shanghai, China.; Shanghai Clinical Research Center for Aging and Medicine, 200040 Shanghai, China.; Center of Community-Based Health Research, Fudan University, 200040 Shanghai, China.
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              Text: 2026 Jun 24
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