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Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.

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Title: Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.
Authors: Tian Y; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China., Miao M; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China., Lei Y; Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China., Yin Y; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China., Chang C; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China., Xin S; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China. iheartxsl@163.com., Zheng M; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.
Source: Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2026 Jul 07. Date of Electronic Publication: 2026 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy Country of Publication: United States NLM ID: 8712220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7241 (Electronic) Linking ISSN: 09203206 NLM ISO Abbreviation: Cardiovasc Drugs Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-7241
DOI:10.1007/s10557-026-07905-3