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Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.

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Title: Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.
Authors: Tian Y; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China., Miao M; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China., Lei Y; Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China., Yin Y; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China., Chang C; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China., Xin S; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China. iheartxsl@163.com., Zheng M; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.
Source: Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2026 Jul 07. Date of Electronic Publication: 2026 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy Country of Publication: United States NLM ID: 8712220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7241 (Electronic) Linking ISSN: 09203206 NLM ISO Abbreviation: Cardiovasc Drugs Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.
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  Data: <searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China.<br /><searchLink fieldCode="AU" term="%22Miao+M%22">Miao M</searchLink>; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China.<br /><searchLink fieldCode="AU" term="%22Chang+C%22">Chang C</searchLink>; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China.<br /><searchLink fieldCode="AU" term="%22Xin+S%22">Xin S</searchLink>; Department of Cardiology, Handan First Hospital, Handan, 056000, Hebei, China. iheartxsl@163.com.<br /><searchLink fieldCode="AU" term="%22Zheng+M%22">Zheng M</searchLink>; Department of Cardiology, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei Key Laboratory of Heart and Metabolism, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.; Hebei International Joint Research Center for Structural Heart Disease, Shijiazhuang, 050031, Hebei, China. mzheng@hebmu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic+For+The+International+Society+For+Cardiovascular+Pharmacotherapy%22">Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8712220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7241 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209203206%22">09203206 </searchLink><i>NLM ISO Abbreviation: </i>Cardiovasc Drugs Ther <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1007/s10557-026-07905-3
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression.
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            NameFull: Tian Y
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            NameFull: Miao M
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            NameFull: Lei Y
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            NameFull: Yin Y
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            NameFull: Chang C
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            NameFull: Xin S
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          Dates:
            – D: 07
              M: 07
              Text: 2026 Jul 07
              Type: published
              Y: 2026
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            – Type: issn-electronic
              Value: 1573-7241
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            – TitleFull: Cardiovascular drugs and therapy
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