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Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons.

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Title: Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons.
Authors: Gu J; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Fan C; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Xiang S; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Yang L; Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China., Liu J; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Si Y; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Zhu B; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Sun Y; Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China., Ding C; Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China.; School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China., Cao S; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China., Ye J; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.
Source: PLoS pathogens [PLoS Pathog] 2026 Jul 07; Vol. 22 (7), pp. e1014335. Date of Electronic Publication: 2026 Jul 07 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons.
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  Data: <searchLink fieldCode="AU" term="%22Gu+J%22">Gu J</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Fan+C%22">Fan C</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Xiang+S%22">Xiang S</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Si+Y%22">Si Y</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Zhu+B%22">Zhu B</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ding+C%22">Ding C</searchLink>; Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China.; School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Cao+S%22">Cao S</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Ye+J%22">Ye J</searchLink>; National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China.; Hubei Hongshan Laboratory, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 Jul 07; Vol. 22 (7), pp. e1014335. <i>Date of Electronic Publication: </i>2026 Jul 07 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE
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        Value: 10.1371/journal.ppat.1014335
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      – Code: eng
        Text: English
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      – TitleFull: Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons.
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              Text: 2026 Jul 07
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