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Upadacitinib enhances platelet procoagulant responses in a subset of healthy individuals and patients with SLE: a pilot study.

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Title: Upadacitinib enhances platelet procoagulant responses in a subset of healthy individuals and patients with SLE: a pilot study.
Authors: Tsegai V; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada., Lawal H; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada., John C; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Akinrinade I; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Duncan S; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada., Dufour A; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Barber CEH; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada., Hazlewood G; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada., Choi MY; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada., Agbani EO; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada ejaife.agbani@ucalgary.ca.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
Source: Lupus science & medicine [Lupus Sci Med] 2026 Jul 07; Vol. 13 (2). Date of Electronic Publication: 2026 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Country of Publication: England NLM ID: 101633705 Publication Model: Electronic Cited Medium: Print ISSN: 2053-8790 (Print) Linking ISSN: 20538790 NLM ISO Abbreviation: Lupus Sci Med Subsets: MEDLINE
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  Data: Upadacitinib enhances platelet procoagulant responses in a subset of healthy individuals and patients with SLE: a pilot study.
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  Data: <searchLink fieldCode="AU" term="%22Tsegai+V%22">Tsegai V</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Lawal+H%22">Lawal H</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22John+C%22">John C</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Akinrinade+I%22">Akinrinade I</searchLink>; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Duncan+S%22">Duncan S</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Dufour+A%22">Dufour A</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Barber+CEH%22">Barber CEH</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Hazlewood+G%22">Hazlewood G</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Choi+MY%22">Choi MY</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada.; Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Agbani+EO%22">Agbani EO</searchLink>; McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada ejaife.agbani@ucalgary.ca.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101633705%22">Lupus science & medicine</searchLink> [Lupus Sci Med] 2026 Jul 07; Vol. 13 (2). <i>Date of Electronic Publication: </i>2026 Jul 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ%22">BMJ </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101633705 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2053-8790 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220538790%22">20538790 </searchLink><i>NLM ISO Abbreviation: </i>Lupus Sci Med <i>Subsets: </i>MEDLINE
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        Value: 10.1136/lupus-2026-001983
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        Text: English
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      – TitleFull: Upadacitinib enhances platelet procoagulant responses in a subset of healthy individuals and patients with SLE: a pilot study.
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            – D: 07
              M: 07
              Text: 2026 Jul 07
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              Y: 2026
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