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Immediate post-injury HMGB1 neutralization prevents synaptic dysfunction in burn and hindlimb unloaded rats.

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Title: Immediate post-injury HMGB1 neutralization prevents synaptic dysfunction in burn and hindlimb unloaded rats.
Authors: Sreenivasa Murthy SGS; Mitchell Center for Neurodegenerative Disease, The University of Texas Medical Branch at Galveston, TX, United States.; Department of Neurology, The University of Texas Medical Branch at Galveston, TX, United States., Törő G; Department of Surgery, The University of Texas Medical Branch at Galveston, TX, United States., Wyrick A; Department of Microbiology & Immunology, The University of Texas Medical Branch at Galveston, TX, United States., El Ayadi A; Department of Surgery, The University of Texas Medical Branch at Galveston, TX, United States., Wolf SE; Department of Surgery, The University of Texas Medical Branch at Galveston, TX, United States., Garg NJ; Department of Microbiology & Immunology, The University of Texas Medical Branch at Galveston, TX, United States., Krishnan B; Mitchell Center for Neurodegenerative Disease, The University of Texas Medical Branch at Galveston, TX, United States.; Department of Neurology, The University of Texas Medical Branch at Galveston, TX, United States., Song J; Department of Surgery, The University of Texas Medical Branch at Galveston, TX, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 23; Vol. 17, pp. 1867953. Date of Electronic Publication: 2026 Jun 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1867953