Immune activation induced by FOLR2+ decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion.

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Title: Immune activation induced by FOLR2+ decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion.
Authors: Chen SM; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Li MY; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Yang YX; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Liu N; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Cao XY; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Zhao HB; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Zhu XY; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China., Li MQ; Department of Reproductive Immunology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China., Xie F; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.; Medical Center of Diagnosis and Treatment for Cervical Diseases, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 23; Vol. 17, pp. 1852410. Date of Electronic Publication: 2026 Jun 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Immune activation induced by FOLR2<superscript>+</superscript> decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion.
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  Data: <searchLink fieldCode="AU" term="%22Chen+SM%22">Chen SM</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+MY%22">Li MY</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+YX%22">Yang YX</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Cao+XY%22">Cao XY</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+HB%22">Zhao HB</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhu+XY%22">Zhu XY</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+MQ%22">Li MQ</searchLink>; Department of Reproductive Immunology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xie+F%22">Xie F</searchLink>; Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.; Medical Center of Diagnosis and Treatment for Cervical Diseases, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 23; Vol. 17, pp. 1852410. <i>Date of Electronic Publication: </i>2026 Jun 23 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.3389/fimmu.2026.1852410
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        Text: English
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        StartPage: 1852410
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      – TitleFull: Immune activation induced by FOLR2+ decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion.
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            – D: 23
              M: 06
              Text: 2026 Jun 23
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              Y: 2026
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