Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress.
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| Title: | Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress. |
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| Authors: | Gigas J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA., Meadow ME; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA., Guo J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Lan C; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Hillpot E; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Martinez JC; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Tombline G; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Bellomio P; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Rivera-Almodóvar V; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Welle KA; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Swovick K; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Hryhorenko JR; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Ablaeva J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Ghaemmaghami S; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Seluanov A; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu., Gorbunova V; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu. |
| Source: | GeroScience [Geroscience] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42417966 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gigas+J%22">Gigas J</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Meadow+ME%22">Meadow ME</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Guo+J%22">Guo J</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Lan+C%22">Lan C</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Hillpot+E%22">Hillpot E</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+JC%22">Martinez JC</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Tombline+G%22">Tombline G</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Bellomio+P%22">Bellomio P</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Rivera-Almodóvar+V%22">Rivera-Almodóvar V</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Welle+KA%22">Welle KA</searchLink>; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Swovick+K%22">Swovick K</searchLink>; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Hryhorenko+JR%22">Hryhorenko JR</searchLink>; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Ablaeva+J%22">Ablaeva J</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Ghaemmaghami+S%22">Ghaemmaghami S</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA.<br /><searchLink fieldCode="AU" term="%22Seluanov+A%22">Seluanov A</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu.<br /><searchLink fieldCode="AU" term="%22Gorbunova+V%22">Gorbunova V</searchLink>; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2026 Jul 08. <i>Date of Electronic Publication: </i>2026 Jul 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42417966 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11357-026-02389-3 Languages: – Code: eng Text: English Titles: – TitleFull: Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gigas J – PersonEntity: Name: NameFull: Meadow ME – PersonEntity: Name: NameFull: Guo J – PersonEntity: Name: NameFull: Lan C – PersonEntity: Name: NameFull: Hillpot E – PersonEntity: Name: NameFull: Martinez JC – PersonEntity: Name: NameFull: Tombline G – PersonEntity: Name: NameFull: Bellomio P – PersonEntity: Name: NameFull: Rivera-Almodóvar V – PersonEntity: Name: NameFull: Welle KA – PersonEntity: Name: NameFull: Swovick K – PersonEntity: Name: NameFull: Hryhorenko JR – PersonEntity: Name: NameFull: Ablaeva J – PersonEntity: Name: NameFull: Ghaemmaghami S – PersonEntity: Name: NameFull: Seluanov A – PersonEntity: Name: NameFull: Gorbunova V IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 07 Text: 2026 Jul 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2509-2723 Titles: – TitleFull: GeroScience Type: main |
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