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From Clinical Heterogeneity to National Standardization in Liver Transplantation for Perihilar Cholangiocarcinoma: The LITALHICA Protocol.

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Title: From Clinical Heterogeneity to National Standardization in Liver Transplantation for Perihilar Cholangiocarcinoma: The LITALHICA Protocol.
Authors: Gringeri E; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Furlanetto A; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Nieddu E; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Romagnoli R; General Surgery 2U-Liver Transplant Unit, City of Health and Science University Hospital of Turin, Turin, Italy., Gruttadauria S; Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, Mediterranean Institute for Transplantation and Advanced Specialized Therapies, University of Pittsburgh Medical Center in Italy, Palermo, Italy.; Department of Surgery and Medical and Surgical Specialties, University of Catania, Catania, Italy., Ghinolfi D; Division of Hepatic Surgery and Liver Transplantation, Pisa University Hospital, Pisa, Italy., De Carlis LG; School of Medicine, University of Milano-Bicocca, Milan, Italy., Cescon M; Department of General Surgery and Transplantation, IRCCS, Bologna University Hospital, University of Bologna, Bologna, Italy., Ettorre GM; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Italy., Baccarani U; Department of Medicine, University of Udine, Liver Transplant Center ASUFC Udine, Udine, Italy., Vivarelli M; Hepatobiliary, Pancreatic and Transplantation Surgery, Polytechnic University of Marche, AUO delle Marche, Ancona, Italy., Pinelli D; School of Medicine, University of Milano-Bicocca, Milan, Italy.; Department of Organ Failure and Transplantation, Ospedale Papa Giovanni XXIII, Bergamo, Italy., Carraro A; Liver Transplant Unit, Department of Surgery and Oncology, University Hospital Trust of Verona, Verona, Italy., Agnes S; Department of Surgery, Transplantation Service, Catholic University of the Sacred Heart, Foundation A. Gemelli Hospital, Rome, Italy., Andorno E; Department of Hepatobiliary and Pancreatic Surgery and Liver Transplantation Unit, A.O.U. S. Martino [S. Martino University Hospital], Genoa, Italy., Di Benedetto F; Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy., Mazzaferro V; HPB Surgery and Liver Transplantation Unit, Department of Oncology, University of Milan and Department of Surgery, National Cancer Institute, IRCCS, Milan, Italy., Quintini C; General and Liver Transplant Surgery Unit, Milan Polyclinic, Milan, Italy., Rossi M; General Surgery and Organ Transplantation, Sapienza University of Rome, Umberto I Polyclinic of Rome, Rome, Italy., Tandoi F; Hepatobiliary and Liver Transplant Unit, Department of Precision and Regenerative Medicine and Ionian Area, University Hospital of Bari, Bari, Italy., Tisone G; Department of Surgical Sciences, HPB and Transplant Unit, University of Rome Tor Vergata, Rome, Italy., Vennarecci G; Hepatobiliary Surgery and Liver Transplant Center, AORN Cardarelli hospital, Naples, Italy., Zamboni F; General and Hepatic Transplantation Surgery Unit, Department of Surgery, A.O.B. Brotzu, Cagliari, Italy., Botton M; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Rosso E; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Naldini C; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy., Lanari J; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy., Soldà C; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Bergamo F; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Gambato M; Gastroenterology Unit, University Hospital of Padova, Padova, Italy., De Conti G; Radiology Unit, Padova University Hospital, Padova, Italy., Lonardi S; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Burra P; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.; Gastroenterology Unit, University Hospital of Padova, Padova, Italy., Trapani S; Italian National Transplant Center, National Institute of Health, Rome, Italy., Feltrin G; Italian National Transplant Center, National Institute of Health, Rome, Italy., Cillo U; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.
Source: Transplantation [Transplantation] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-6080 (Electronic) Linking ISSN: 00411337 NLM ISO Abbreviation: Transplantation Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: From Clinical Heterogeneity to National Standardization in Liver Transplantation for Perihilar Cholangiocarcinoma: The LITALHICA Protocol.
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  Data: <searchLink fieldCode="AU" term="%22Gringeri+E%22">Gringeri E</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Furlanetto+A%22">Furlanetto A</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Nieddu+E%22">Nieddu E</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Romagnoli+R%22">Romagnoli R</searchLink>; General Surgery 2U-Liver Transplant Unit, City of Health and Science University Hospital of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Gruttadauria+S%22">Gruttadauria S</searchLink>; Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, Mediterranean Institute for Transplantation and Advanced Specialized Therapies, University of Pittsburgh Medical Center in Italy, Palermo, Italy.; Department of Surgery and Medical and Surgical Specialties, University of Catania, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Ghinolfi+D%22">Ghinolfi D</searchLink>; Division of Hepatic Surgery and Liver Transplantation, Pisa University Hospital, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22De+Carlis+LG%22">De Carlis LG</searchLink>; School of Medicine, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cescon+M%22">Cescon M</searchLink>; Department of General Surgery and Transplantation, IRCCS, Bologna University Hospital, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ettorre+GM%22">Ettorre GM</searchLink>; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Baccarani+U%22">Baccarani U</searchLink>; Department of Medicine, University of Udine, Liver Transplant Center ASUFC Udine, Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Vivarelli+M%22">Vivarelli M</searchLink>; Hepatobiliary, Pancreatic and Transplantation Surgery, Polytechnic University of Marche, AUO delle Marche, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Pinelli+D%22">Pinelli D</searchLink>; School of Medicine, University of Milano-Bicocca, Milan, Italy.; Department of Organ Failure and Transplantation, Ospedale Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Carraro+A%22">Carraro A</searchLink>; Liver Transplant Unit, Department of Surgery and Oncology, University Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Agnes+S%22">Agnes S</searchLink>; Department of Surgery, Transplantation Service, Catholic University of the Sacred Heart, Foundation A. Gemelli Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Andorno+E%22">Andorno E</searchLink>; Department of Hepatobiliary and Pancreatic Surgery and Liver Transplantation Unit, A.O.U. S. Martino [S. Martino University Hospital], Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Benedetto+F%22">Di Benedetto F</searchLink>; Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzaferro+V%22">Mazzaferro V</searchLink>; HPB Surgery and Liver Transplantation Unit, Department of Oncology, University of Milan and Department of Surgery, National Cancer Institute, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Quintini+C%22">Quintini C</searchLink>; General and Liver Transplant Surgery Unit, Milan Polyclinic, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+M%22">Rossi M</searchLink>; General Surgery and Organ Transplantation, Sapienza University of Rome, Umberto I Polyclinic of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Tandoi+F%22">Tandoi F</searchLink>; Hepatobiliary and Liver Transplant Unit, Department of Precision and Regenerative Medicine and Ionian Area, University Hospital of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Tisone+G%22">Tisone G</searchLink>; Department of Surgical Sciences, HPB and Transplant Unit, University of Rome Tor Vergata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Vennarecci+G%22">Vennarecci G</searchLink>; Hepatobiliary Surgery and Liver Transplant Center, AORN Cardarelli hospital, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Zamboni+F%22">Zamboni F</searchLink>; General and Hepatic Transplantation Surgery Unit, Department of Surgery, A.O.B. Brotzu, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Botton+M%22">Botton M</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Rosso+E%22">Rosso E</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Naldini+C%22">Naldini C</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Lanari+J%22">Lanari J</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Soldà+C%22">Soldà C</searchLink>; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bergamo+F%22">Bergamo F</searchLink>; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Gambato+M%22">Gambato M</searchLink>; Gastroenterology Unit, University Hospital of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22De+Conti+G%22">De Conti G</searchLink>; Radiology Unit, Padova University Hospital, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Lonardi+S%22">Lonardi S</searchLink>; Medical Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Burra+P%22">Burra P</searchLink>; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.; Gastroenterology Unit, University Hospital of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Trapani+S%22">Trapani S</searchLink>; Italian National Transplant Center, National Institute of Health, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Feltrin+G%22">Feltrin G</searchLink>; Italian National Transplant Center, National Institute of Health, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cillo+U%22">Cillo U</searchLink>; Hepato-Bilio-Pancreatic Surgery and Liver Transplantation Unit, Padova University Hospital, Padova, Italy.; Department of Surgery, Oncology, Gastroenterology, Padova University, Padova, Italy.
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