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A structure-based epitope tagging approach identifies vulnerable sites on the malarial P36-P52 protein complex for antibody-mediated neutralization of Plasmodium sporozoites.

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Title: A structure-based epitope tagging approach identifies vulnerable sites on the malarial P36-P52 protein complex for antibody-mediated neutralization of Plasmodium sporozoites.
Authors: Das S; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France., Boeykens L; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium., Loubens M; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France., Marinach C; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France., Briquet S; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France., De Vocht L; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium., Pintelon I; Laboratory of Cell Biology and Histology and the Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Wilrijk, Belgium., Timmermans JP; Laboratory of Cell Biology and Histology and the Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Wilrijk, Belgium., Sterckx YG; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium., Silvie O; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.
Source: PLoS pathogens [PLoS Pathog] 2026 Jul 08; Vol. 22 (7), pp. e1014418. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A structure-based epitope tagging approach identifies vulnerable sites on the malarial P36-P52 protein complex for antibody-mediated neutralization of Plasmodium sporozoites.
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  Data: <searchLink fieldCode="AU" term="%22Das+S%22">Das S</searchLink>; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Boeykens+L%22">Boeykens L</searchLink>; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Loubens+M%22">Loubens M</searchLink>; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Marinach+C%22">Marinach C</searchLink>; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Briquet+S%22">Briquet S</searchLink>; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22De+Vocht+L%22">De Vocht L</searchLink>; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Pintelon+I%22">Pintelon I</searchLink>; Laboratory of Cell Biology and Histology and the Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Timmermans+JP%22">Timmermans JP</searchLink>; Laboratory of Cell Biology and Histology and the Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Sterckx+YG%22">Sterckx YG</searchLink>; Laboratory of Medical Biochemistry and Infla-Med Centre of Excellence, University of Antwerp, Wilrijk, Belgium.<br /><searchLink fieldCode="AU" term="%22Silvie+O%22">Silvie O</searchLink>; Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 Jul 08; Vol. 22 (7), pp. e1014418. <i>Date of Electronic Publication: </i>2026 Jul 08 (<i>Print Publication: </i>2026).
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              Text: 2026 Jul 08
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