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Calcium influx through T-type calcium channels regulates secondary necrosis and inflammation through recruitment of ATG9A-mediated membrane repair.

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Title: Calcium influx through T-type calcium channels regulates secondary necrosis and inflammation through recruitment of ATG9A-mediated membrane repair.
Authors: Audi OF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Ozkocak DC; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Johnson C; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia., Shi B; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Santavanond JP; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Vella CL; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Hildebrand JM; The Walter and Eliza Hall Institute, Parkville, VIC, 3052, Australia., Sharples R; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia., Le QT; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Cheng Sim L; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia., Baxter AA; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Hulett MD; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Poon IKH; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia. i.poon@latrobe.edu.au., Phan TK; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia. kha.phan@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia. kha.phan@latrobe.edu.au.
Source: Cell death & disease [Cell Death Dis] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: Calcium influx through T-type calcium channels regulates secondary necrosis and inflammation through recruitment of ATG9A-mediated membrane repair.
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  Data: <searchLink fieldCode="AU" term="%22Audi+OF%22">Audi OF</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Ozkocak+DC%22">Ozkocak DC</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Johnson+C%22">Johnson C</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Shi+B%22">Shi B</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Santavanond+JP%22">Santavanond JP</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Vella+CL%22">Vella CL</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Hildebrand+JM%22">Hildebrand JM</searchLink>; The Walter and Eliza Hall Institute, Parkville, VIC, 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Sharples+R%22">Sharples R</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Le+QT%22">Le QT</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Cheng+Sim+L%22">Cheng Sim L</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Baxter+AA%22">Baxter AA</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Hulett+MD%22">Hulett MD</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.<br /><searchLink fieldCode="AU" term="%22Poon+IKH%22">Poon IKH</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia. i.poon@latrobe.edu.au.<br /><searchLink fieldCode="AU" term="%22Phan+TK%22">Phan TK</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Bundoora, VIC, 3086, Australia. kha.phan@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia. kha.phan@latrobe.edu.au.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-09070-9
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