Efficacy and safety of eribulin mesylate vs. docetaxel or paclitaxel, combined with trastuzumab and pertuzumab, as first-line treatment for HER2-positive locally advanced or metastatic breast cancer: updated subgroup analyses of JBCRG-M06/EMERALD.
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| Title: | Efficacy and safety of eribulin mesylate vs. docetaxel or paclitaxel, combined with trastuzumab and pertuzumab, as first-line treatment for HER2-positive locally advanced or metastatic breast cancer: updated subgroup analyses of JBCRG-M06/EMERALD. |
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| Authors: | Masuda N; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. nmasuda@alpha.ocn.ne.jp., Saji S; Department of Medical Oncology, Fukushima Medical University, Fukushima, Japan., Kojima Y; Institute for Clinical Genetics and Genomics / Division of Breast Surgical Oncology, Department of Surgery, Showa Medical University, Tokyo, Japan., Kitada M; Department of Breast Disease Center, Asahikawa Medical University Hospital, Hokkaido, Japan., Tada H; Department of Surgery, Division of Breast and Endocrine Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan.; Division of Breast and Endocrine Surgery, Tohoku Medical and Pharmaceutical University, Miyagi, Japan., Iwasa T; Department of Medical Oncology, Kindai University Hospital, Osaka, Japan., Koizumi K; Department of Surgery 1, Division of Breast Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan., Iwatani T; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine, Kanagawa, Japan., Sagara Y; Department of Breast and Thyroid Surgical Oncology, Social Medical Corporation Hakuaikai, Sagara Hospital, Kagoshima, Japan., Kuwayama T; Department of Breast Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan., Shimoda M; Department of Breast and Endocrine Surgery, Hyogo Medical University Hospital, Hyogo, Japan., Sasada T; Department of Breast and Endocrine Surgery, NHO Higashihiroshima Medical Center, Hiroshima, Japan., Tsugawa K; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine, Kanagawa, Japan., Kawaguchi Y; Department of Breast Surgery, Asahi University Hospital, Gifu, Japan., Shimomura A; Department of Breast and Medical Oncology, National Center for Global Health and Medicine, Tokyo, Japan., Yamaguchi T; Division of Biostatistics, Tohoku University Graduate School of Medicine, Miyagi, Japan., Hasegawa H; Medical HQs, Eisai Co., Ltd, Tokyo, Japan., Osaka S; Medical HQs, Eisai Co., Ltd, Tokyo, Japan., Morita S; Department of Biomedical Statistics and Bioinformatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Yamashita T; Department of Breast Surgery and Oncology, Kanagawa Cancer Center, Kanagawa, Japan. |
| Source: | Breast cancer research and treatment [Breast Cancer Res Treat] 2026 Jul 08; Vol. 218 (1). Date of Electronic Publication: 2026 Jul 08. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III |
| Journal Info: | Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42420599 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and safety of eribulin mesylate vs. docetaxel or paclitaxel, combined with trastuzumab and pertuzumab, as first-line treatment for HER2-positive locally advanced or metastatic breast cancer: updated subgroup analyses of JBCRG-M06/EMERALD. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Masuda+N%22">Masuda N</searchLink>; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. nmasuda@alpha.ocn.ne.jp.<br /><searchLink fieldCode="AU" term="%22Saji+S%22">Saji S</searchLink>; Department of Medical Oncology, Fukushima Medical University, Fukushima, Japan.<br /><searchLink fieldCode="AU" term="%22Kojima+Y%22">Kojima Y</searchLink>; Institute for Clinical Genetics and Genomics / Division of Breast Surgical Oncology, Department of Surgery, Showa Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kitada+M%22">Kitada M</searchLink>; Department of Breast Disease Center, Asahikawa Medical University Hospital, Hokkaido, Japan.<br /><searchLink fieldCode="AU" term="%22Tada+H%22">Tada H</searchLink>; Department of Surgery, Division of Breast and Endocrine Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan.; Division of Breast and Endocrine Surgery, Tohoku Medical and Pharmaceutical University, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Iwasa+T%22">Iwasa T</searchLink>; Department of Medical Oncology, Kindai University Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Koizumi+K%22">Koizumi K</searchLink>; Department of Surgery 1, Division of Breast Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Iwatani+T%22">Iwatani T</searchLink>; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Sagara+Y%22">Sagara Y</searchLink>; Department of Breast and Thyroid Surgical Oncology, Social Medical Corporation Hakuaikai, Sagara Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Kuwayama+T%22">Kuwayama T</searchLink>; Department of Breast Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoda+M%22">Shimoda M</searchLink>; Department of Breast and Endocrine Surgery, Hyogo Medical University Hospital, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Sasada+T%22">Sasada T</searchLink>; Department of Breast and Endocrine Surgery, NHO Higashihiroshima Medical Center, Hiroshima, Japan.<br /><searchLink fieldCode="AU" term="%22Tsugawa+K%22">Tsugawa K</searchLink>; Department of Breast and Endocrine Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+Y%22">Kawaguchi Y</searchLink>; Department of Breast Surgery, Asahi University Hospital, Gifu, Japan.<br /><searchLink fieldCode="AU" term="%22Shimomura+A%22">Shimomura A</searchLink>; Department of Breast and Medical Oncology, National Center for Global Health and Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+T%22">Yamaguchi T</searchLink>; Division of Biostatistics, Tohoku University Graduate School of Medicine, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+H%22">Hasegawa H</searchLink>; Medical HQs, Eisai Co., Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Osaka+S%22">Osaka S</searchLink>; Medical HQs, Eisai Co., Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Morita+S%22">Morita S</searchLink>; Department of Biomedical Statistics and Bioinformatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yamashita+T%22">Yamashita T</searchLink>; Department of Breast Surgery and Oncology, Kanagawa Cancer Center, Kanagawa, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228111104%22">Breast cancer research and treatment</searchLink> [Breast Cancer Res Treat] 2026 Jul 08; Vol. 218 (1). <i>Date of Electronic Publication: </i>2026 Jul 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8111104 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7217 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676806%22">01676806 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res Treat <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42420599 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10549-026-08004-5 Languages: – Code: eng Text: English Titles: – TitleFull: Efficacy and safety of eribulin mesylate vs. docetaxel or paclitaxel, combined with trastuzumab and pertuzumab, as first-line treatment for HER2-positive locally advanced or metastatic breast cancer: updated subgroup analyses of JBCRG-M06/EMERALD. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Masuda N – PersonEntity: Name: NameFull: Saji S – PersonEntity: Name: NameFull: Kojima Y – PersonEntity: Name: NameFull: Kitada M – PersonEntity: Name: NameFull: Tada H – PersonEntity: Name: NameFull: Iwasa T – PersonEntity: Name: NameFull: Koizumi K – PersonEntity: Name: NameFull: Iwatani T – PersonEntity: Name: NameFull: Sagara Y – PersonEntity: Name: NameFull: Kuwayama T – PersonEntity: Name: NameFull: Shimoda M – PersonEntity: Name: NameFull: Sasada T – PersonEntity: Name: NameFull: Tsugawa K – PersonEntity: Name: NameFull: Kawaguchi Y – PersonEntity: Name: NameFull: Shimomura A – PersonEntity: Name: NameFull: Yamaguchi T – PersonEntity: Name: NameFull: Hasegawa H – PersonEntity: Name: NameFull: Osaka S – PersonEntity: Name: NameFull: Morita S – PersonEntity: Name: NameFull: Yamashita T IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 07 Text: 2026 Jul 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1573-7217 Numbering: – Type: volume Value: 218 – Type: issue Value: 1 Titles: – TitleFull: Breast cancer research and treatment Type: main |
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