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Plant-derived mitochondria mitigate aging-related neurodegeneration by reprogramming microglial mitochondrial energy metabolism.

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Title: Plant-derived mitochondria mitigate aging-related neurodegeneration by reprogramming microglial mitochondrial energy metabolism.
Authors: Teng Y; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA. yun.teng@louisville.edu., Luo C; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Central Laboratory, The Affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, 223300, Jiangsu, China., Xu Q; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA., Mu J; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Teng L; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA., Qian H; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Huang Y; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Liu M; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Breast and Thyroid Surgery, The Affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, 223300, Jiangsu, China., Zhang L; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Park JW; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, 40202, USA., Hwang JY; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Kong M; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, 40202, USA., Yan J; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA., Merchant ML; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA., Zhang HG; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. h0zhan17@louisville.edu.; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA. h0zhan17@louisville.edu.; Robley Rex Veterans Affairs Medical Center, Louisville, KY, 40206, USA. h0zhan17@louisville.edu.
Source: Translational neurodegeneration [Transl Neurodegener] 2026 Jul 08; Vol. 15 (1). Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Plant-derived mitochondria mitigate aging-related neurodegeneration by reprogramming microglial mitochondrial energy metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Teng+Y%22">Teng Y</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA. yun.teng@louisville.edu.<br /><searchLink fieldCode="AU" term="%22Luo+C%22">Luo C</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Central Laboratory, The Affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, 223300, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Mu+J%22">Mu J</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Teng+L%22">Teng L</searchLink>; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Qian+H%22">Qian H</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Breast and Thyroid Surgery, The Affiliated Huai'an First People's Hospital of Nanjing Medical University, Huai'an, 223300, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Park+JW%22">Park JW</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+JY%22">Hwang JY</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Kong+M%22">Kong M</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, SPHIS, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Merchant+ML%22">Merchant ML</searchLink>; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+HG%22">Zhang HG</searchLink>; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. h0zhan17@louisville.edu.; Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, CTRB Room 309, 505 S. Hancock Street, Louisville, KY, 40202, USA. h0zhan17@louisville.edu.; Robley Rex Veterans Affairs Medical Center, Louisville, KY, 40206, USA. h0zhan17@louisville.edu.
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  Data: <searchLink fieldCode="JN" term="%22101591861%22">Translational neurodegeneration</searchLink> [Transl Neurodegener] 2026 Jul 08; Vol. 15 (1). <i>Date of Electronic Publication: </i>2026 Jul 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101591861 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2047-9158 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479158%22">20479158 </searchLink><i>NLM ISO Abbreviation: </i>Transl Neurodegener <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s40035-026-00565-1
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Plant-derived mitochondria mitigate aging-related neurodegeneration by reprogramming microglial mitochondrial energy metabolism.
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              Text: 2026 Jul 08
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              Y: 2026
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            – TitleFull: Translational neurodegeneration
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