Addition of Intra-Arterial Therapy to Immunotherapy Improves Outcomes in Unresectable Hepatocellular Carcinoma: Taiwan Multicenter Cohort Study.

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Title: Addition of Intra-Arterial Therapy to Immunotherapy Improves Outcomes in Unresectable Hepatocellular Carcinoma: Taiwan Multicenter Cohort Study.
Authors: Lee TY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Lee PC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Shen YC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan., Hsu WF; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Lai SW; Division of Hematology and Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei City, Taiwan., Chang CW; Division of Gastroenterology and Hepatology, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan., Su YY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital, and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan., Su TH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu County, Taiwan., Lin PT; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Dai CY; Hepato-Biliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan., Hsu CS; Center for Digestive Medicine, Department of Medical Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.; Liver Diseases Prevention and Treatment Center, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan., Chen SC; Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Rau KM; Department of Hematology Oncology, E-DA Cancer Hospital, School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan., Lee IC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Jhan SR; Department of Medical Imaging, Taichung Veterans General Hospital, Taichung City, Taiwan., Liu TH; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan., Lai HC; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Taichung Municipal Geriatric Rehabilitation and Comprehensive Hospital, Taichung, Taiwan., Wang TE; Division of Gastroenterology and Hepatology, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan., Lin SM; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Liang PC; Hepato-Biliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan., Tseng CH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-DA Cancer Hospital, School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan., Chang PY; Department of Medical Imaging, Taichung Veterans General Hospital, Taichung City, Taiwan.; Department of Post-Baccalaureate Medicine, National Chung Hsing University, Taichung, Taiwan., Wu SC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Wang HW; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan., Lee SW; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Post-Baccalaureate Medicine, National Chung Hsing University, Taichung, Taiwan., Huang YH; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Corporate Authors: TRG investigators
Source: Liver cancer [Liver Cancer] 2026 May 05. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: S. Karger Country of Publication: Switzerland NLM ID: 101597993 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2235-1795 (Print) Linking ISSN: 16645553 NLM ISO Abbreviation: Liver Cancer
Database: MEDLINE Ultimate
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  Data: Addition of Intra-Arterial Therapy to Immunotherapy Improves Outcomes in Unresectable Hepatocellular Carcinoma: Taiwan Multicenter Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Lee+TY%22">Lee TY</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+PC%22">Lee PC</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+YC%22">Shen YC</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+WF%22">Hsu WF</searchLink>; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+SW%22">Lai SW</searchLink>; Division of Hematology and Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CW%22">Chang CW</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+YY%22">Su YY</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital, and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+TH%22">Su TH</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu County, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PT%22">Lin PT</searchLink>; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Dai+CY%22">Dai CY</searchLink>; Hepato-Biliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; College of Medicine, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CS%22">Hsu CS</searchLink>; Center for Digestive Medicine, Department of Medical Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.; Liver Diseases Prevention and Treatment Center, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+SC%22">Chen SC</searchLink>; Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Rau+KM%22">Rau KM</searchLink>; Department of Hematology Oncology, E-DA Cancer Hospital, School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+IC%22">Lee IC</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jhan+SR%22">Jhan SR</searchLink>; Department of Medical Imaging, Taichung Veterans General Hospital, Taichung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+TH%22">Liu TH</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+HC%22">Lai HC</searchLink>; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Taichung Municipal Geriatric Rehabilitation and Comprehensive Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+TE%22">Wang TE</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, MacKay Medical University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SM%22">Lin SM</searchLink>; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liang+PC%22">Liang PC</searchLink>; Hepato-Biliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tseng+CH%22">Tseng CH</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-DA Cancer Hospital, School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+PY%22">Chang PY</searchLink>; Department of Medical Imaging, Taichung Veterans General Hospital, Taichung City, Taiwan.; Department of Post-Baccalaureate Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SC%22">Wu SC</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+HW%22">Wang HW</searchLink>; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+SW%22">Lee SW</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Post-Baccalaureate Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YH%22">Huang YH</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101597993%22">Liver cancer</searchLink> [Liver Cancer] 2026 May 05. <i>Date of Electronic Publication: </i>2026 May 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22S%2E+Karger%22">S. Karger </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101597993 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2235-1795 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216645553%22">16645553 </searchLink><i>NLM ISO Abbreviation: </i>Liver Cancer
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42421887
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