Efficacy and safety of the single-dose pegylated G-CSF vs. daily G-CSF for peripheral blood stem cells mobilization in donors: a multicenter, randomized controlled trial.

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Title: Efficacy and safety of the single-dose pegylated G-CSF vs. daily G-CSF for peripheral blood stem cells mobilization in donors: a multicenter, randomized controlled trial.
Authors: Li J; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Zhou S; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Li X; Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China., Ma X; Department of Epidemiology, College of Preventive Medicine, Army Military Medical University, Chongqing, China., Wang S; Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China., Zhang Y; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Lou S; Department of Hematology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China., Rao J; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Wang P; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Zhu L; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Chen T; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Xiang X; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Gao S; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Yao H; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Kong P; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Gao L; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Zhang C; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Zhang X; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China., Gao L; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 24; Vol. 17, pp. 1737252. Date of Electronic Publication: 2026 Jun 24 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of the single-dose pegylated G-CSF vs. daily G-CSF for peripheral blood stem cells mobilization in donors: a multicenter, randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Department of Epidemiology, College of Preventive Medicine, Army Military Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Lou+S%22">Lou S</searchLink>; Department of Hematology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Rao+J%22">Rao J</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Xiang+X%22">Xiang X</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Yao+H%22">Yao H</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Kong+P%22">Kong P</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Medical Center of Hematology, Institute of Science Innovation for Blood Ecology and Intelligent Cells, The Second Affiliated Hospital of Army Medical University, Chongqing, China.; Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 24; Vol. 17, pp. 1737252. <i>Date of Electronic Publication: </i>2026 Jun 24 (<i>Print Publication: </i>2026).
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