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Site-specific differences in Nectin-4 expression and associated immune contexture in advanced urothelial carcinoma: implications for Nectin-4-targeted ADCs.

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Title: Site-specific differences in Nectin-4 expression and associated immune contexture in advanced urothelial carcinoma: implications for Nectin-4-targeted ADCs.
Authors: Hsueh FJ; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan., Wang CC; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan., Hsu CL; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan., Wu SC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Guo JC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Chuang CH; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Chueh SC; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan., Tsai YC; Department of Oncology, National Taiwan University Hospital, Taipei 100225, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.
Source: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2026 Jul 07; Vol. 18, pp. 17588359261463147. Date of Electronic Publication: 2026 Jul 07 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Sage Country of Publication: England NLM ID: 101510808 Publication Model: eCollection Cited Medium: Print ISSN: 1758-8340 (Print) Linking ISSN: 17588340 NLM ISO Abbreviation: Ther Adv Med Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Site-specific differences in Nectin-4 expression and associated immune contexture in advanced urothelial carcinoma: implications for Nectin-4-targeted ADCs.
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  Data: <searchLink fieldCode="AU" term="%22Hsueh+FJ%22">Hsueh FJ</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CC%22">Wang CC</searchLink>; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CL%22">Hsu CL</searchLink>; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SC%22">Wu SC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Guo+JC%22">Guo JC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuang+CH%22">Chuang CH</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chueh+SC%22">Chueh SC</searchLink>; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+YC%22">Tsai YC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei 100225, Taiwan.; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101510808%22">Therapeutic advances in medical oncology</searchLink> [Ther Adv Med Oncol] 2026 Jul 07; Vol. 18, pp. 17588359261463147. <i>Date of Electronic Publication: </i>2026 Jul 07 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage%22">Sage </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101510808 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1758-8340 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217588340%22">17588340 </searchLink><i>NLM ISO Abbreviation: </i>Ther Adv Med Oncol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1177/17588359261463147
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              Text: 2026 Jul 07
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