View in EDS

Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.

Saved in:
Bibliographic Details
Title: Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.
Authors: Burn J; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK; The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. Electronic address: john.burn@newcastle.ac.uk., Borthwick GM; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK., Elliott F; Institute of Medical Research, University of Leeds, Leeds, UK., Macrae F; Royal Melbourne Hospital, Parkville, VIC, Australia., Ong KR; Birmingham Women's and Children's NHS Trust, Department of Clinical Genetics, Birmingham, UK., Kraus AC; Leeds Clinical Genomics Service, Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK., Arber N; Tel Aviv Medical Center, Tel Aviv, Israel., Mecklin JP; Department of Education and Research, The Wellbeing Services County of Central Finland, Jyväskylä, Finland and Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Alonso A; Genomic Medicine Unit, Navarrabiomed-Universidad Pública de Navarra (UPNA) Hospital Universitario de Navarra (HUN), IdiSNA, Pamplona, Navarra, Spain., Woodward ER; Division of Evolution Infection and Genomic Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK., Evans DG; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Murray A; Wales Genomics Health Centre, Cardiff, UK., Snape K; St George's University Hospitals NHS Foundation Trust, London, UK., Cleaver RE; Peninsula Clinical Genetics, Royal Devon and Exeter (Heavitree), Exeter, UK., Shaw A; Clinical Genetics, Guy's Hospital, London, UK., Thomas HJW; St Marks Hospital, Harrow, Middlesex, UK; Faculty of Medicine, Imperial College London, London, UK., Kumar AV; North East Thames Regional Genetics Service, Great Ormond Street Hospital, London, UK., Halliday D; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Side LE; University Hospital Southampton NHS Trust, Southampton General Hospital, Southampton, Hampshire, UK., Harrison RE; Nottingham University Hospitals, City Campus, Nottingham, UK., Davidson R; West of Scotland Centre for Genomic Medicine, Queen Elizabeth University Hospital, Glasgow, UK., Armstrong R; Department of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Cook J; Sheffield Children's Hospital, Sheffield, UK., Hart R; Liverpool Women's Hospital, Liverpool, UK., Morrison PJ; Patrick G Johnston Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, UK., Barwell JG; Clinical Genetics, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK., Donaldson A; Clinical Genetics Service, St Michaels Hospital, Bristol, UK., Kemp Z; The Royal Marsden NHS Trust, London, UK., Murray J; South East Scotland Clinical Genetics Service, Western General Hospital, Edinburgh, UK., Miedzybrodzka Z; Clinical Genetics Centre, Ashgrove House Aberdeen Royal Infirmary, Aberdeen, UK., Pottinger C; All Wales Medical Genomics Service, Wrexham Maelor Hospital, Wrexham, UK., Berg J; University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Gallon R; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK., Bishop DT; Institute of Medical Research, University of Leeds, Leeds, UK. Electronic address: d.t.bishop@leeds.ac.uk.
Corporate Authors: CaPP3 co-investigators
Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2026 Jul 09. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42425127
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Burn+J%22">Burn J</searchLink>; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK; The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. Electronic address: john.burn@newcastle.ac.uk.<br /><searchLink fieldCode="AU" term="%22Borthwick+GM%22">Borthwick GM</searchLink>; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Elliott+F%22">Elliott F</searchLink>; Institute of Medical Research, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Macrae+F%22">Macrae F</searchLink>; Royal Melbourne Hospital, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ong+KR%22">Ong KR</searchLink>; Birmingham Women's and Children's NHS Trust, Department of Clinical Genetics, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Kraus+AC%22">Kraus AC</searchLink>; Leeds Clinical Genomics Service, Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Arber+N%22">Arber N</searchLink>; Tel Aviv Medical Center, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Mecklin+JP%22">Mecklin JP</searchLink>; Department of Education and Research, The Wellbeing Services County of Central Finland, Jyväskylä, Finland and Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Alonso+A%22">Alonso A</searchLink>; Genomic Medicine Unit, Navarrabiomed-Universidad Pública de Navarra (UPNA) Hospital Universitario de Navarra (HUN), IdiSNA, Pamplona, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22Woodward+ER%22">Woodward ER</searchLink>; Division of Evolution Infection and Genomic Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Evans+DG%22">Evans DG</searchLink>; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Murray+A%22">Murray A</searchLink>; Wales Genomics Health Centre, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Snape+K%22">Snape K</searchLink>; St George's University Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Cleaver+RE%22">Cleaver RE</searchLink>; Peninsula Clinical Genetics, Royal Devon and Exeter (Heavitree), Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Shaw+A%22">Shaw A</searchLink>; Clinical Genetics, Guy's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+HJW%22">Thomas HJW</searchLink>; St Marks Hospital, Harrow, Middlesex, UK; Faculty of Medicine, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kumar+AV%22">Kumar AV</searchLink>; North East Thames Regional Genetics Service, Great Ormond Street Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Halliday+D%22">Halliday D</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Side+LE%22">Side LE</searchLink>; University Hospital Southampton NHS Trust, Southampton General Hospital, Southampton, Hampshire, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+RE%22">Harrison RE</searchLink>; Nottingham University Hospitals, City Campus, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Davidson+R%22">Davidson R</searchLink>; West of Scotland Centre for Genomic Medicine, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Armstrong+R%22">Armstrong R</searchLink>; Department of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cook+J%22">Cook J</searchLink>; Sheffield Children's Hospital, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Hart+R%22">Hart R</searchLink>; Liverpool Women's Hospital, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Morrison+PJ%22">Morrison PJ</searchLink>; Patrick G Johnston Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Barwell+JG%22">Barwell JG</searchLink>; Clinical Genetics, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Donaldson+A%22">Donaldson A</searchLink>; Clinical Genetics Service, St Michaels Hospital, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Kemp+Z%22">Kemp Z</searchLink>; The Royal Marsden NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Murray+J%22">Murray J</searchLink>; South East Scotland Clinical Genetics Service, Western General Hospital, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Miedzybrodzka+Z%22">Miedzybrodzka Z</searchLink>; Clinical Genetics Centre, Ashgrove House Aberdeen Royal Infirmary, Aberdeen, UK.<br /><searchLink fieldCode="AU" term="%22Pottinger+C%22">Pottinger C</searchLink>; All Wales Medical Genomics Service, Wrexham Maelor Hospital, Wrexham, UK.<br /><searchLink fieldCode="AU" term="%22Berg+J%22">Berg J</searchLink>; University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Gallon+R%22">Gallon R</searchLink>; Newcastle University Translational & Clinical Research Institute, Centre for Life, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Bishop+DT%22">Bishop DT</searchLink>; Institute of Medical Research, University of Leeds, Leeds, UK. Electronic address: d.t.bishop@leeds.ac.uk.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22CaPP3+co-investigators%22">CaPP3 co-investigators</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101690683%22">The lancet. Gastroenterology & hepatology</searchLink> [Lancet Gastroenterol Hepatol] 2026 Jul 09. <i>Date of Electronic Publication: </i>2026 Jul 09.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101690683 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2468-1253 (Electronic) <i>NLM ISO Abbreviation: </i>Lancet Gastroenterol Hepatol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42425127
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/S2468-1253(26)00114-7
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Burn J
      – PersonEntity:
          Name:
            NameFull: Borthwick GM
      – PersonEntity:
          Name:
            NameFull: Elliott F
      – PersonEntity:
          Name:
            NameFull: Macrae F
      – PersonEntity:
          Name:
            NameFull: Ong KR
      – PersonEntity:
          Name:
            NameFull: Kraus AC
      – PersonEntity:
          Name:
            NameFull: Arber N
      – PersonEntity:
          Name:
            NameFull: Mecklin JP
      – PersonEntity:
          Name:
            NameFull: Alonso A
      – PersonEntity:
          Name:
            NameFull: Woodward ER
      – PersonEntity:
          Name:
            NameFull: Evans DG
      – PersonEntity:
          Name:
            NameFull: Murray A
      – PersonEntity:
          Name:
            NameFull: Snape K
      – PersonEntity:
          Name:
            NameFull: Cleaver RE
      – PersonEntity:
          Name:
            NameFull: Shaw A
      – PersonEntity:
          Name:
            NameFull: Thomas HJW
      – PersonEntity:
          Name:
            NameFull: Kumar AV
      – PersonEntity:
          Name:
            NameFull: Halliday D
      – PersonEntity:
          Name:
            NameFull: Side LE
      – PersonEntity:
          Name:
            NameFull: Harrison RE
      – PersonEntity:
          Name:
            NameFull: Davidson R
      – PersonEntity:
          Name:
            NameFull: Armstrong R
      – PersonEntity:
          Name:
            NameFull: Cook J
      – PersonEntity:
          Name:
            NameFull: Hart R
      – PersonEntity:
          Name:
            NameFull: Morrison PJ
      – PersonEntity:
          Name:
            NameFull: Barwell JG
      – PersonEntity:
          Name:
            NameFull: Donaldson A
      – PersonEntity:
          Name:
            NameFull: Kemp Z
      – PersonEntity:
          Name:
            NameFull: Murray J
      – PersonEntity:
          Name:
            NameFull: Miedzybrodzka Z
      – PersonEntity:
          Name:
            NameFull: Pottinger C
      – PersonEntity:
          Name:
            NameFull: Berg J
      – PersonEntity:
          Name:
            NameFull: Gallon R
      – PersonEntity:
          Name:
            NameFull: Bishop DT
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 09
              M: 07
              Text: 2026 Jul 09
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2468-1253
          Titles:
            – TitleFull: The lancet. Gastroenterology & hepatology
              Type: main
ResultId 1