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Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.

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Title: Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.
Authors: Garot P; Cardiovascular European Research Center (CERC), 7 Rue du Théatre, 91300, Massy, France.; Institut Cardiovasculaire Paris-Sud (ICPS), Hôpital Privé Jacques Cartier, Ramsay-Santé, 6 avenue du Noyer Lambert, Massy 91300, France., Mehran R; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA., de Backer O; The Heart Center, Rigshospitalet, Copenhagen, Denmark., Freeman JV; Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA., Wunderlich N; Department of Cardiology, Asklepios Klinik Langen, Langen, Germany., Hibbert B; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Tzikas A; Second Department of Cardiology, Faculty of Health Sciences, School of Medicine, General Hospital 'Hippokration', Aristotle University of Thessaloniki, Thessaloniki, Greece., Nair D; Division of Cardiac Electrophysiology, St.Bernards Medical Center & Arrhythmia Research Group, Jonesboro, AR, USA., Berti S; Department of Cardiology, Fondazione Toscana Gabriele Monasterio, Massa, Italy., Saw J; Division of Cardiology, Vancouver General Hospital, Vancouver, BC, Canada., Freixa X; Department of Cardiology, Cardiovascular Institute, Hospital Clínic, Barcelona, Spain., Doshi SK; Pacific Heart Institute, Cedars Sinai Health System, Santa Monica, CA, USA., Cruz-Gonzalez I; University Hospital Salamanca, CIBER-CV, IBSAL, Salamanca, Spain., Coylewright M; Heart and Vascular Center, Essentia Health, Duluth, MN, USA., Aminian A; Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium., Price MJ; Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, CA, USA., Räber L; Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland., Yao X; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Sanchis L; Department of Cardiology, Cardiovascular Institute, Hospital Clínic, Barcelona, Spain., Ruff CT; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Landmesser U; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Charité University Medicine Berlin, Berlin, Germany., Lakkireddy D; Kansas City Heart Rhythm Institute and Research Foundation, HCA Midwest Health, Overland Park, KS, USA., Ellis CR; Division of Cardiovascular Medicine, Vanderbilt Heart Institute, Nashville, TN, USA., Alasnag M; Cardiac Center, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia., Yamamoto M; Cardiology, Toyohashi Heart Center, Aichi, Japan., Ferro EG; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Iwamoto S; Pharmaceuticals and Medical Devices Agency, Chiyoda-ku, Tokyo, Japan., Shiba T; Pharmaceuticals and Medical Devices Agency, Chiyoda-ku, Tokyo, Japan., Jin Y; Independent Clinical Expert for EU Notified Body., Schmidt B; Cardioangiologisches Centrum Bethanien, Agaplesion Markus Krankenhaus, Frankfurt, Germany., Jagadeesan V; Department of Cardiology, West Virginia University, Morgantown, WV, USA., Reddy VY; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA., Hildick-Smith D; Sussex Cardiac Centre, University Hospitals Sussex, Brighton, UK., Oliva A; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA., Krucoff MW; Division of Cardiology, Department of Medicine, Duke University, Duke Clinical Research Institute, Durham, NC, USA., Spitzer E; Cardialysis, Rotterdam, The Netherlands., Nielsen-Kudsk JE; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark., Gibson CM; Harvard Medical School, Baim Institute for Clinical Research, Boston, MA, USA., Gurol EM; Department of Neurology, Massachusetts General Brigham, Harvard Medical School, Boston, MA, USA., Cutlip DE; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Leon MB; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY, USA.; Cardiovascular Research Foundation, NewYork, NY, USA., Holmes DR Jr; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Morice MC; Cardiovascular European Research Center (CERC), 7 Rue du Théatre, 91300, Massy, France., Alkhouli M; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Source: European heart journal [Eur Heart J] 2026 Jul 09. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.
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  Data: <searchLink fieldCode="AU" term="%22Garot+P%22">Garot P</searchLink>; Cardiovascular European Research Center (CERC), 7 Rue du Théatre, 91300, Massy, France.; Institut Cardiovasculaire Paris-Sud (ICPS), Hôpital Privé Jacques Cartier, Ramsay-Santé, 6 avenue du Noyer Lambert, Massy 91300, France.<br /><searchLink fieldCode="AU" term="%22Mehran+R%22">Mehran R</searchLink>; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA.<br /><searchLink fieldCode="AU" term="%22de+Backer+O%22">de Backer O</searchLink>; The Heart Center, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Freeman+JV%22">Freeman JV</searchLink>; Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wunderlich+N%22">Wunderlich N</searchLink>; Department of Cardiology, Asklepios Klinik Langen, Langen, Germany.<br /><searchLink fieldCode="AU" term="%22Hibbert+B%22">Hibbert B</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tzikas+A%22">Tzikas A</searchLink>; Second Department of Cardiology, Faculty of Health Sciences, School of Medicine, General Hospital 'Hippokration', Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Nair+D%22">Nair D</searchLink>; Division of Cardiac Electrophysiology, St.Bernards Medical Center & Arrhythmia Research Group, Jonesboro, AR, USA.<br /><searchLink fieldCode="AU" term="%22Berti+S%22">Berti S</searchLink>; Department of Cardiology, Fondazione Toscana Gabriele Monasterio, Massa, Italy.<br /><searchLink fieldCode="AU" term="%22Saw+J%22">Saw J</searchLink>; Division of Cardiology, Vancouver General Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Freixa+X%22">Freixa X</searchLink>; Department of Cardiology, Cardiovascular Institute, Hospital Clínic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Doshi+SK%22">Doshi SK</searchLink>; Pacific Heart Institute, Cedars Sinai Health System, Santa Monica, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cruz-Gonzalez+I%22">Cruz-Gonzalez I</searchLink>; University Hospital Salamanca, CIBER-CV, IBSAL, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Coylewright+M%22">Coylewright M</searchLink>; Heart and Vascular Center, Essentia Health, Duluth, MN, USA.<br /><searchLink fieldCode="AU" term="%22Aminian+A%22">Aminian A</searchLink>; Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium.<br /><searchLink fieldCode="AU" term="%22Price+MJ%22">Price MJ</searchLink>; Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Räber+L%22">Räber L</searchLink>; Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yao+X%22">Yao X</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Sanchis+L%22">Sanchis L</searchLink>; Department of Cardiology, Cardiovascular Institute, Hospital Clínic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ruff+CT%22">Ruff CT</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Landmesser+U%22">Landmesser U</searchLink>; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Charité University Medicine Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lakkireddy+D%22">Lakkireddy D</searchLink>; Kansas City Heart Rhythm Institute and Research Foundation, HCA Midwest Health, Overland Park, KS, USA.<br /><searchLink fieldCode="AU" term="%22Ellis+CR%22">Ellis CR</searchLink>; Division of Cardiovascular Medicine, Vanderbilt Heart Institute, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Alasnag+M%22">Alasnag M</searchLink>; Cardiac Center, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; 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Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hildick-Smith+D%22">Hildick-Smith D</searchLink>; Sussex Cardiac Centre, University Hospitals Sussex, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Oliva+A%22">Oliva A</searchLink>; Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, NewYork, NY, USA.<br /><searchLink fieldCode="AU" term="%22Krucoff+MW%22">Krucoff MW</searchLink>; Division of Cardiology, Department of Medicine, Duke University, Duke Clinical Research Institute, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Spitzer+E%22">Spitzer E</searchLink>; Cardialysis, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nielsen-Kudsk+JE%22">Nielsen-Kudsk JE</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Gibson+CM%22">Gibson CM</searchLink>; Harvard Medical School, Baim Institute for Clinical Research, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gurol+EM%22">Gurol EM</searchLink>; Department of Neurology, Massachusetts General Brigham, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cutlip+DE%22">Cutlip DE</searchLink>; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Leon+MB%22">Leon MB</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY, USA.; Cardiovascular Research Foundation, NewYork, NY, USA.<br /><searchLink fieldCode="AU" term="%22Holmes+DR+Jr%22">Holmes DR Jr</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Morice+MC%22">Morice MC</searchLink>; Cardiovascular European Research Center (CERC), 7 Rue du Théatre, 91300, Massy, France.<br /><searchLink fieldCode="AU" term="%22Alkhouli+M%22">Alkhouli M</searchLink>; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
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