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A head-to-head comparison of abatacept and adalimumab in adults with early and dual seropositive rheumatoid arthritis plus HLA-DRB1 shared epitope: results from the randomised phase 3 AMPLIFIED trial.

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Title: A head-to-head comparison of abatacept and adalimumab in adults with early and dual seropositive rheumatoid arthritis plus HLA-DRB1 shared epitope: results from the randomised phase 3 AMPLIFIED trial.
Authors: Emery P; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. Electronic address: p.emery@leeds.ac.uk., Weinblatt ME; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bykerk VP; Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA., Cope AP; Centre for Rheumatic Diseases, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Tanaka Y; University of Occupational and Environmental Health, Kitakyushu, Japan., Citera G; Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina., Nash P; Griffith University, Brisbane, Queensland, Australia., Burmester GR; Charité-Universitätsmedizin Berlin, Berlin, Germany., Dornic Q; Bristol Myers Squibb, Princeton, NJ, USA., Kelly S; Bristol Myers Squibb, Princeton, NJ, USA., Eddy N; Bristol Myers Squibb, Princeton, NJ, USA., Liu J; Bristol Myers Squibb, Princeton, NJ, USA., Schafer P; Bristol Myers Squibb, Princeton, NJ, USA., Buckner J; Benaroya Research Institute, Seattle, WA, USA., Maldonado MA; Bristol Myers Squibb, Princeton, NJ, USA.
Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2026 Jul 09. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Country of Publication: United States NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A head-to-head comparison of abatacept and adalimumab in adults with early and dual seropositive rheumatoid arthritis plus HLA-DRB1 shared epitope: results from the randomised phase 3 AMPLIFIED trial.
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  Data: <searchLink fieldCode="AU" term="%22Emery+P%22">Emery P</searchLink>; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. Electronic address: p.emery@leeds.ac.uk.<br /><searchLink fieldCode="AU" term="%22Weinblatt+ME%22">Weinblatt ME</searchLink>; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bykerk+VP%22">Bykerk VP</searchLink>; Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cope+AP%22">Cope AP</searchLink>; Centre for Rheumatic Diseases, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; University of Occupational and Environmental Health, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Citera+G%22">Citera G</searchLink>; Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Nash+P%22">Nash P</searchLink>; Griffith University, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Burmester+GR%22">Burmester GR</searchLink>; Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Dornic+Q%22">Dornic Q</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+S%22">Kelly S</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Eddy+N%22">Eddy N</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Schafer+P%22">Schafer P</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Buckner+J%22">Buckner J</searchLink>; Benaroya Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Maldonado+MA%22">Maldonado MA</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.
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              Text: 2026 Jul 09
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