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Lauric Acid- and BDSF-Derived N-Acyl Sulfonamides as Potent Antibiofilm and Antivirulence Agents against Staphylococcus aureus.

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Title: Lauric Acid- and BDSF-Derived N-Acyl Sulfonamides as Potent Antibiofilm and Antivirulence Agents against Staphylococcus aureus.
Authors: Kim YG; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea., O'Driscoll M; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland., Horgan C; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland., Boya BR; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea., Sim M; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea., Lee JH; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea., Lee J; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea., O'Sullivan TP; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland.
Source: Journal of medicinal chemistry [J Med Chem] 2026 Jul 23; Vol. 69 (14), pp. 17473-17486. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kim+YG%22">Kim YG</searchLink>; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22O'Driscoll+M%22">O'Driscoll M</searchLink>; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland.<br /><searchLink fieldCode="AU" term="%22Horgan+C%22">Horgan C</searchLink>; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland.<br /><searchLink fieldCode="AU" term="%22Boya+BR%22">Boya BR</searchLink>; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sim+M%22">Sim M</searchLink>; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22O'Sullivan+TP%22">O'Sullivan TP</searchLink>; School of Chemistry, University College Cork, Cork T12 YN60, Ireland.; School of Pharmacy, University College Cork, Cork T12 YN60, Ireland.; Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2026 Jul 23; Vol. 69 (14), pp. 17473-17486. <i>Date of Electronic Publication: </i>2026 Jul 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.jmedchem.6c01485
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              Text: 2026 Jul 23
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