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Resolving human α versus β cell fate allocation for the generation of stem cell-derived islets.

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Title: Resolving human α versus β cell fate allocation for the generation of stem cell-derived islets.
Authors: Akgün Canan M; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; School of Medicine, Technical University of Munich, Munich, Germany.; Stem Cell Institute, Ankara University, Ankara, Türkiye.; Integrated Technologies Research Center (BÜTAM), Ankara University, Ankara, Türkiye., Cozzitorto C; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Sterr M; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; School of Medicine, Technical University of Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Saber L; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Setyono ESA; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Dema A; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Kozawa K; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Wang X; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Merl-Pham J; Metabolomics and Proteomics Core, Helmholtz Center Munich, Munich, Germany., Greisle T; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Burtscher I; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; School of Medicine, Technical University of Munich, Munich, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; School of Medicine, Technical University of Munich, Munich, Germany. heiko.lickert@helmholtz-munich.de.; German Center for Diabetes Research (DZD), Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.
Source: Nature communications [Nat Commun] 2026 Jul 09; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-75255-7