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Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women.

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Title: Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women.
Authors: Li Z; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Wang S; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Mao X; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Zhang X; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Wei P; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Chen L; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China., Xue L; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China. ltxgxh@163.com., Ruan Z; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China. ziyunruan@163.com.; School of Basic Medicine, Guangxi Key Laboratory of Chinese Medicine Foundation Research, Guangxi University of Chinese Medicine, Nanning, Guangxi, China. ziyunruan@163.com.
Source: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2026 Jul; Vol. 33 (7), pp. 1432-1446. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women.
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Mao+X%22">Mao X</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Wei+P%22">Wei P</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Xue+L%22">Xue L</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China. ltxgxh@163.com.<br /><searchLink fieldCode="AU" term="%22Ruan+Z%22">Ruan Z</searchLink>; Reproductive Medical and Genetic Center, The People's Hospital of Guangxi Zhuang Autonoumous Region, Nanning, Guangxi, China. ziyunruan@163.com.; School of Basic Medicine, Guangxi Key Laboratory of Chinese Medicine Foundation Research, Guangxi University of Chinese Medicine, Nanning, Guangxi, China. ziyunruan@163.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101291249 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1933-7205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219337191%22">19337191 </searchLink><i>NLM ISO Abbreviation: </i>Reprod Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s43032-026-02145-0
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        Text: English
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      – TitleFull: Integrated Metabolomic and Transcriptomic Profiling Reveals a Distinct Pathological Aging State in Diminished Ovarian Reserve of Advanced Reproductive-Age Women.
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              M: 07
              Text: 2026 Jul
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