Antibodies against interleukin-10 receptor reduce IL-6 and TNF-α levels and increase TGF-β levels in patients with severe fever with thrombocytopenia syndrome virus and SARS-CoV-2 infection.

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Title: Antibodies against interleukin-10 receptor reduce IL-6 and TNF-α levels and increase TGF-β levels in patients with severe fever with thrombocytopenia syndrome virus and SARS-CoV-2 infection.
Authors: Kang SY; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Yoo JR; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Bae E; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Kim J; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Park Y; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea., Kim M; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Kim M; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Ro HJ; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Hwang D; School of Biological Science, Seoul National University, Seoul, Republic of Korea., Lee JY; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Cho D; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Nguyen HC; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Hallam HJ; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Heo ST; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Cho NH; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee KM; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea., Letizia AG; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Lee KH; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 25; Vol. 17, pp. 1828107. Date of Electronic Publication: 2026 Jun 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1828107