Antibodies against interleukin-10 receptor reduce IL-6 and TNF-α levels and increase TGF-β levels in patients with severe fever with thrombocytopenia syndrome virus and SARS-CoV-2 infection.

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Title: Antibodies against interleukin-10 receptor reduce IL-6 and TNF-α levels and increase TGF-β levels in patients with severe fever with thrombocytopenia syndrome virus and SARS-CoV-2 infection.
Authors: Kang SY; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Yoo JR; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Bae E; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Kim J; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Park Y; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea., Kim M; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Kim M; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Ro HJ; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Hwang D; School of Biological Science, Seoul National University, Seoul, Republic of Korea., Lee JY; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Cho D; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea., Nguyen HC; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Hallam HJ; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Heo ST; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea., Cho NH; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee KM; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea., Letizia AG; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Lee KH; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 25; Vol. 17, pp. 1828107. Date of Electronic Publication: 2026 Jun 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Antibodies against interleukin-10 receptor reduce IL-6 and TNF-α levels and increase TGF-β levels in patients with severe fever with thrombocytopenia syndrome virus and SARS-CoV-2 infection.
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  Data: <searchLink fieldCode="AU" term="%22Kang+SY%22">Kang SY</searchLink>; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+JR%22">Yoo JR</searchLink>; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+E%22">Bae E</searchLink>; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+Y%22">Park Y</searchLink>; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ro+HJ%22">Ro HJ</searchLink>; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+D%22">Hwang D</searchLink>; School of Biological Science, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+D%22">Cho D</searchLink>; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nguyen+HC%22">Nguyen HC</searchLink>; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Hallam+HJ%22">Hallam HJ</searchLink>; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Heo+ST%22">Heo ST</searchLink>; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+NH%22">Cho NH</searchLink>; Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KM%22">Lee KM</searchLink>; Department of Biochemistry, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Letizia+AG%22">Letizia AG</searchLink>; US Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Hanyang University College of Medicine and Intercollege, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 25; Vol. 17, pp. 1828107. <i>Date of Electronic Publication: </i>2026 Jun 25 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 25
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