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Maintenance DNA methylation is necessary for age-related alterations in regulatory T cell transcriptional and DNA methylation signatures.

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Title: Maintenance DNA methylation is necessary for age-related alterations in regulatory T cell transcriptional and DNA methylation signatures.
Authors: Gurkan JK; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Liu Q; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Flores CPR; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Helmin KA; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Ryan DH; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Health Sciences Integrated Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Joudi AM; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Ulrich BJ; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Abdala-Valencia H; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Steinert EM; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA., Singer BD; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Simpson Querrey Lung Institute for Translational Science (SQ LIFTS), Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 29. Date of Electronic Publication: 2026 Jun 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Maintenance DNA methylation is necessary for age-related alterations in regulatory T cell transcriptional and DNA methylation signatures.
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  Data: <searchLink fieldCode="AU" term="%22Gurkan+JK%22">Gurkan JK</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Flores+CPR%22">Flores CPR</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Driskill Graduate Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Helmin+KA%22">Helmin KA</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Ryan+DH%22">Ryan DH</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Health Sciences Integrated Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Joudi+AM%22">Joudi AM</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Ulrich+BJ%22">Ulrich BJ</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Abdala-Valencia+H%22">Abdala-Valencia H</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Steinert+EM%22">Steinert EM</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.<br /><searchLink fieldCode="AU" term="%22Singer+BD%22">Singer BD</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.; Simpson Querrey Lung Institute for Translational Science (SQ LIFTS), Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Jun 29. <i>Date of Electronic Publication: </i>2026 Jun 29.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.64898/2026.06.24.733005
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        Text: English
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            – D: 29
              M: 06
              Text: 2026 Jun 29
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