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Ontological Analysis of Brain Proteostasis Highlights the Sex-Dependent Trajectory of ApoE Isoform-Specific Regulation.

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Title: Ontological Analysis of Brain Proteostasis Highlights the Sex-Dependent Trajectory of ApoE Isoform-Specific Regulation.
Authors: Denos AEA; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Clark E; Department of Statistics, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Earls NE; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Paymard N; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Elison JM; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Jones BS; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Smith EG; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Colman EG; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Nielsen CO; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Sorensen M; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Moran NG; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Wells JG; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Burlett RS; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Vickers ES; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Garrard CT; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Brown JR; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Brown KL; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Matute JD; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Daouahi W; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Poulson MF; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Tolley HD; Department of Statistics, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America., Price JC; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Jones+BS%22">Jones BS</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+EG%22">Smith EG</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Colman+EG%22">Colman EG</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Nielsen+CO%22">Nielsen CO</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Sorensen+M%22">Sorensen M</searchLink>; 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Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Brown+KL%22">Brown KL</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Matute+JD%22">Matute JD</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Daouahi+W%22">Daouahi W</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Poulson+MF%22">Poulson MF</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Tolley+HD%22">Tolley HD</searchLink>; Department of Statistics, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Price+JC%22">Price JC</searchLink>; Department of Chemistry and Biochemistry, College of Computational, Physical, and Mathematical Sciences, Brigham Young University, Provo, Utah, United States of America.
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