CRISPR activation screens identify core protein-dependent regulation of heparan sulfate sulfation and ligand specificity.

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Bibliographic Details
Title: CRISPR activation screens identify core protein-dependent regulation of heparan sulfate sulfation and ligand specificity.
Authors: Moore JC; Complex Carbohydrate Research Center, University of Georgia, Athens, GA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA., Takeuchi H; Complex Carbohydrate Research Center, University of Georgia, Athens, GA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA., Nguyen C; Complex Carbohydrate Research Center, University of Georgia, Athens, GA., Huang C; Complex Carbohydrate Research Center, University of Georgia, Athens, GA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA., Chapla D; Complex Carbohydrate Research Center, University of Georgia, Athens, GA., Basu A; Complex Carbohydrate Research Center, University of Georgia, Athens, GA., Wang Z; Glycan Therapeutics Corp, Raleigh, NC., Liu J; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC., Moremen KW; Complex Carbohydrate Research Center, University of Georgia, Athens, GA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA., Weiss RJ; Complex Carbohydrate Research Center, University of Georgia, Athens, GA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.06.29.735380