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Shared trans-ancestry architecture of HLA-mediated disease risk in the All of Us Research Program.

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Title: Shared trans-ancestry architecture of HLA-mediated disease risk in the All of Us Research Program.
Authors: Ahn K; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709., House JS; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709., Burkholder A; Office of Environmental Science Cyberinfrastructure, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Research Triangle Park, NC 27709., Tran TC; Precision Health Informatics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892., Breeyear JH; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709., Justice CM; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709., Durney J; Department of Biology, Brigham Young University, Provo, UT, 84602., Jones AM; Department of Biology, Brigham Young University, Provo, UT, 84602., Reyes PS; Department of Biology, Brigham Young University, Provo, UT, 84602., Bailey MH; Department of Biology, Brigham Young University, Provo, UT, 84602., Davis MF; Department of Biology, Brigham Young University, Provo, UT, 84602.; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, 84602., Vicenti AT; Department of Pharmacy Practice and Science, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721., Karnes JH; Department of Pharmacy Practice and Science, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721., Hollenbach JA; Department of Neurology and Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158., Fargo DC; Office of Environmental Science Cyberinfrastructure, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Research Triangle Park, NC 27709., Ginsburg GS; All of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD 20892., Woychik RP; Office of the Director, National Institutes of Health, Bethesda, MD 20892., Denny JC; Precision Health Informatics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.; All of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD 20892., Motsinger-Reif AA; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ahn+K%22">Ahn K</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22House+JS%22">House JS</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22Burkholder+A%22">Burkholder A</searchLink>; Office of Environmental Science Cyberinfrastructure, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22Tran+TC%22">Tran TC</searchLink>; Precision Health Informatics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Breeyear+JH%22">Breeyear JH</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22Justice+CM%22">Justice CM</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22Durney+J%22">Durney J</searchLink>; Department of Biology, Brigham Young University, Provo, UT, 84602.<br /><searchLink fieldCode="AU" term="%22Jones+AM%22">Jones AM</searchLink>; Department of Biology, Brigham Young University, Provo, UT, 84602.<br /><searchLink fieldCode="AU" term="%22Reyes+PS%22">Reyes PS</searchLink>; Department of Biology, Brigham Young University, Provo, UT, 84602.<br /><searchLink fieldCode="AU" term="%22Bailey+MH%22">Bailey MH</searchLink>; Department of Biology, Brigham Young University, Provo, UT, 84602.<br /><searchLink fieldCode="AU" term="%22Davis+MF%22">Davis MF</searchLink>; Department of Biology, Brigham Young University, Provo, UT, 84602.; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, 84602.<br /><searchLink fieldCode="AU" term="%22Vicenti+AT%22">Vicenti AT</searchLink>; Department of Pharmacy Practice and Science, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721.<br /><searchLink fieldCode="AU" term="%22Karnes+JH%22">Karnes JH</searchLink>; Department of Pharmacy Practice and Science, R Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ 85721.<br /><searchLink fieldCode="AU" term="%22Hollenbach+JA%22">Hollenbach JA</searchLink>; Department of Neurology and Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158.<br /><searchLink fieldCode="AU" term="%22Fargo+DC%22">Fargo DC</searchLink>; Office of Environmental Science Cyberinfrastructure, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Research Triangle Park, NC 27709.<br /><searchLink fieldCode="AU" term="%22Ginsburg+GS%22">Ginsburg GS</searchLink>; All of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Woychik+RP%22">Woychik RP</searchLink>; Office of the Director, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; Precision Health Informatics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.; All of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD 20892.<br /><searchLink fieldCode="AU" term="%22Motsinger-Reif+AA%22">Motsinger-Reif AA</searchLink>; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Division of Intramural Research, Research Triangle Park, NC 27709.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 Jun 30. <i>Date of Electronic Publication: </i>2026 Jun 30.
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        Value: 10.64898/2026.06.26.26356709
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