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Anti-inflammatory and antinociceptive effects of a novel 1,5-benzodiazepine derivative in murine models.

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Title: Anti-inflammatory and antinociceptive effects of a novel 1,5-benzodiazepine derivative in murine models.
Authors: El Fatimi H; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco., Khalki H; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco.; Applied Biology for Health, Environment and Sustainable Development Team (BASED), Department of Biology and Geology, Polydisciplinary Faculty of Beni Mellal, Sultan Moulay Slimane University, Beni Mellal, Morocco., Ndayambaje M; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco., Loughzail M; Molecular Chemistry Laboratory, Department of Chemistry, Faculty of Sciences Semlalia, Cadi University Ayyad, BP 2390, 40001, Marrakech, Morocco., Hachimi N; Physiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research Centre, Mohammed V University, Rabat, Morocco., Elaazri H; Physiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research Centre, Mohammed V University, Rabat, Morocco., Baouid A; Molecular Chemistry Laboratory, Department of Chemistry, Faculty of Sciences Semlalia, Cadi University Ayyad, BP 2390, 40001, Marrakech, Morocco., Oudghiri M; Laboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, B.P 2693, Maarif, Casablanca, Morocco., Naya A; Laboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, B.P 2693, Maarif, Casablanca, Morocco., Zaid Y; Laboratory of Materials, Nanotechnology and Environment, Faculty of Sciences, Mohammed V University, 4 Avenue Ibn Battouta, B.P. 1014 RP, Rabat, Morocco., Khalki L; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco. lkhalki@um6ss.ma.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco. lkhalki@um6ss.ma.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jul 10. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anti-inflammatory and antinociceptive effects of a novel 1,5-benzodiazepine derivative in murine models.
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  Data: <searchLink fieldCode="AU" term="%22El+Fatimi+H%22">El Fatimi H</searchLink>; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco.<br /><searchLink fieldCode="AU" term="%22Khalki+H%22">Khalki H</searchLink>; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco.; Applied Biology for Health, Environment and Sustainable Development Team (BASED), Department of Biology and Geology, Polydisciplinary Faculty of Beni Mellal, Sultan Moulay Slimane University, Beni Mellal, Morocco.<br /><searchLink fieldCode="AU" term="%22Ndayambaje+M%22">Ndayambaje M</searchLink>; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco.<br /><searchLink fieldCode="AU" term="%22Loughzail+M%22">Loughzail M</searchLink>; Molecular Chemistry Laboratory, Department of Chemistry, Faculty of Sciences Semlalia, Cadi University Ayyad, BP 2390, 40001, Marrakech, Morocco.<br /><searchLink fieldCode="AU" term="%22Hachimi+N%22">Hachimi N</searchLink>; Physiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research Centre, Mohammed V University, Rabat, Morocco.<br /><searchLink fieldCode="AU" term="%22Elaazri+H%22">Elaazri H</searchLink>; Physiology and Physiopathology Team, Faculty of Sciences, Genomic of Human Pathologies Research Centre, Mohammed V University, Rabat, Morocco.<br /><searchLink fieldCode="AU" term="%22Baouid+A%22">Baouid A</searchLink>; Molecular Chemistry Laboratory, Department of Chemistry, Faculty of Sciences Semlalia, Cadi University Ayyad, BP 2390, 40001, Marrakech, Morocco.<br /><searchLink fieldCode="AU" term="%22Oudghiri+M%22">Oudghiri M</searchLink>; Laboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, B.P 2693, Maarif, Casablanca, Morocco.<br /><searchLink fieldCode="AU" term="%22Naya+A%22">Naya A</searchLink>; Laboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, B.P 2693, Maarif, Casablanca, Morocco.<br /><searchLink fieldCode="AU" term="%22Zaid+Y%22">Zaid Y</searchLink>; Laboratory of Materials, Nanotechnology and Environment, Faculty of Sciences, Mohammed V University, 4 Avenue Ibn Battouta, B.P. 1014 RP, Rabat, Morocco.<br /><searchLink fieldCode="AU" term="%22Khalki+L%22">Khalki L</searchLink>; Mohammed VI University of Sciences and Health (UM6SS), Avenue Mohammed Taieb Naciri, 82403, Casablanca, Morocco. lkhalki@um6ss.ma.; Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Avenue Mohammed Taieb Naciri, 82403, Casablanca, Mohammed, Morocco. lkhalki@um6ss.ma.
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              Text: 2026 Jul 10
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