Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis.

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Title: Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis.
Authors: Li C; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)., Dai Z; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319.; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China., Tang WC; The University of Hong Kong Libraries, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)., Gao Z; The University of Hong Kong Libraries, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)., Chan VKY; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)., Ramirez-Posada M; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States., Kim J; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States., Linos E; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States., Cheung CL; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319., Wong ICK; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong).; School of Pharmacy, Aston University, Birmingham, United Kingdom.; Macau University of Science and Technology, Macau Special Administrative Region, China., Dong D; The Jockey Club School of Public Health and Primary Care (JCSPHPC),The Chinese University of Hong Kong, New Territories, Hong Kong SAR, China (Hong Kong)., To M; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.; Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong).; Shenzhen Clinical Research Center for Rare Diseases, Shenzhen, China., Craig D; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Li X; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319.; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Source: Journal of medical Internet research [J Med Internet Res] 2026 Jul 10; Vol. 28, pp. e85840. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 100959882 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-8871 (Electronic) Linking ISSN: 14388871 NLM ISO Abbreviation: J Med Internet Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).<br /><searchLink fieldCode="AU" term="%22Dai+Z%22">Dai Z</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319.; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Tang+WC%22">Tang WC</searchLink>; The University of Hong Kong Libraries, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).<br /><searchLink fieldCode="AU" term="%22Gao+Z%22">Gao Z</searchLink>; The University of Hong Kong Libraries, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).<br /><searchLink fieldCode="AU" term="%22Chan+VKY%22">Chan VKY</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).<br /><searchLink fieldCode="AU" term="%22Ramirez-Posada+M%22">Ramirez-Posada M</searchLink>; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Linos+E%22">Linos E</searchLink>; Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States.; Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Cheung+CL%22">Cheung CL</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319.<br /><searchLink fieldCode="AU" term="%22Wong+ICK%22">Wong ICK</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong).; School of Pharmacy, Aston University, Birmingham, United Kingdom.; Macau University of Science and Technology, Macau Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Dong+D%22">Dong D</searchLink>; The Jockey Club School of Public Health and Primary Care (JCSPHPC),The Chinese University of Hong Kong, New Territories, Hong Kong SAR, China (Hong Kong).<br /><searchLink fieldCode="AU" term="%22To+M%22">To M</searchLink>; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.; Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong).; Shenzhen Clinical Research Center for Rare Diseases, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Craig+D%22">Craig D</searchLink>; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong).; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road, Hong Kong SAR, China (Hong Kong), 852 2255 3319.; The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
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