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Ligand-independent EPHA2 signaling sustains neural progenitors via ECSIT and NAD.

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Title: Ligand-independent EPHA2 signaling sustains neural progenitors via ECSIT and NAD.
Authors: Diem Nghi T; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., My Nhung TT; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.; Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA., Kim S; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., Yun J; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., Tien NTN; Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea., Lee A; Department of Biochemistry, Daegu Catholic University School of Medicine, Daegu, Republic of Korea., Jung M; Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea., Jang EJ; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., Goo BS; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yoo JY; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., Shin SR; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea., Mun JY; Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea., Park KM; Department of Biochemistry, Daegu Catholic University School of Medicine, Daegu, Republic of Korea., Phuoc Long N; Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan., Park C; Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA., Park SK; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea. skpark@postech.ac.kr.
Source: EMBO reports [EMBO Rep] 2026 Jul 10. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
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  Data: Ligand-independent EPHA2 signaling sustains neural progenitors via ECSIT and NAD<superscript />.
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  Data: <searchLink fieldCode="AU" term="%22Diem+Nghi+T%22">Diem Nghi T</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22My+Nhung+TT%22">My Nhung TT</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.; Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yun+J%22">Yun J</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Tien+NTN%22">Tien NTN</searchLink>; Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Department of Biochemistry, Daegu Catholic University School of Medicine, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+M%22">Jung M</searchLink>; Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+EJ%22">Jang EJ</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Goo+BS%22">Goo BS</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yoo+JY%22">Yoo JY</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+SR%22">Shin SR</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Mun+JY%22">Mun JY</searchLink>; Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+KM%22">Park KM</searchLink>; Department of Biochemistry, Daegu Catholic University School of Medicine, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Phuoc+Long+N%22">Phuoc Long N</searchLink>; Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Park+C%22">Park C</searchLink>; Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Park+SK%22">Park SK</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea. skpark@postech.ac.kr.
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        Value: 10.1038/s44319-026-00858-6
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              Text: 2026 Jul 10
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