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Serum Proteomic Profiling Implicates a Dysregulated Neurohormonal-Inflammatory Axis in Post-Fontan Sinus Tachycardia.

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Title: Serum Proteomic Profiling Implicates a Dysregulated Neurohormonal-Inflammatory Axis in Post-Fontan Sinus Tachycardia.
Authors: Takaesu F; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA.; Biochemistry, Cell and Developmental Biology Graduate Training Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School Emory University Atlanta GA USA., Villarreal DJ; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA., Zhou A; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA., Jimenez MR; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA., Turner ME; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA., Spiess JL; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; West Virginia University School of Medicine Morgantown WV USA., Kievert JC; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA., DeShetler CM; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA., Schwartzman WE; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA., Yates AR; The Heart Center Nationwide Children's Hospital Columbus OH USA.; Department of Pediatrics The Ohio State University College of Medicine Columbus OH USA., Kelly JM; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA.; Department of Pediatrics The Ohio State University College of Medicine Columbus OH USA., Breuer CK; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA., Davis ME; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA.; Children's Heart Research and Outcomes (HeRO) Center Children's Healthcare of Atlanta and Emory University Atlanta GA USA.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 Jul 10, pp. e049852. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Takaesu+F%22">Takaesu F</searchLink>; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA.; Biochemistry, Cell and Developmental Biology Graduate Training Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School Emory University Atlanta GA USA.<br /><searchLink fieldCode="AU" term="%22Villarreal+DJ%22">Villarreal DJ</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Zhou+A%22">Zhou A</searchLink>; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA.<br /><searchLink fieldCode="AU" term="%22Jimenez+MR%22">Jimenez MR</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Turner+ME%22">Turner ME</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Spiess+JL%22">Spiess JL</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; West Virginia University School of Medicine Morgantown WV USA.<br /><searchLink fieldCode="AU" term="%22Kievert+JC%22">Kievert JC</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22DeShetler+CM%22">DeShetler CM</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Schwartzman+WE%22">Schwartzman WE</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Ohio State University College of Medicine Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Yates+AR%22">Yates AR</searchLink>; The Heart Center Nationwide Children's Hospital Columbus OH USA.; Department of Pediatrics The Ohio State University College of Medicine Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Kelly+JM%22">Kelly JM</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA.; Department of Pediatrics The Ohio State University College of Medicine Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Breuer+CK%22">Breuer CK</searchLink>; Center for Regenerative Medicine Abigail Wexner Research Institute at Nationwide Children's Hospital Columbus OH USA.; The Heart Center Nationwide Children's Hospital Columbus OH USA.<br /><searchLink fieldCode="AU" term="%22Davis+ME%22">Davis ME</searchLink>; Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of Medicine Atlanta GA USA.; Children's Heart Research and Outcomes (HeRO) Center Children's Healthcare of Atlanta and Emory University Atlanta GA USA.
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