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Genome-wide DNA methylation analysis in pigs using long-read sequencing unveils high-altitude adaptation and allele-specific regulation.

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Title: Genome-wide DNA methylation analysis in pigs using long-read sequencing unveils high-altitude adaptation and allele-specific regulation.
Authors: Jiang YF; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.; Frontier Technology Research Institute of China Agricultural University in Shenzhen, Shenzhen, 518119, China., Guo Y; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Yao WY; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China., Qiu A; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Wang CL; Key Laboratory of Pig Molecular Quantitative Genetics of Anhui Academy of Agricultural Sciences, Anhui Provincial Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Sciences, Hefei, 230031, China., Xu RH; Key Laboratory of Animal Genetics and Breeding of Zhejiang Province, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China., Zhang Q; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Taian, 271001, China., Fang LZ; Center for Quantitative Genetics and Genomics, Aarhus for University, Aarhus, 8000, Denmark. lingzhao.fang@qgg.au.dk., Ding XD; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. xding@cau.edu.cn.; Frontier Technology Research Institute of China Agricultural University in Shenzhen, Shenzhen, 518119, China. xding@cau.edu.cn.
Source: BMC genomics [BMC Genomics] 2026 Jul 10. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide DNA methylation analysis in pigs using long-read sequencing unveils high-altitude adaptation and allele-specific regulation.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+YF%22">Jiang YF</searchLink>; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.; Frontier Technology Research Institute of China Agricultural University in Shenzhen, Shenzhen, 518119, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Yao+WY%22">Yao WY</searchLink>; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.<br /><searchLink fieldCode="AU" term="%22Qiu+A%22">Qiu A</searchLink>; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.<br /><searchLink fieldCode="AU" term="%22Wang+CL%22">Wang CL</searchLink>; Key Laboratory of Pig Molecular Quantitative Genetics of Anhui Academy of Agricultural Sciences, Anhui Provincial Key Laboratory of Livestock and Poultry Product Safety Engineering, Institute of Animal Husbandry and Veterinary Medicine, Anhui Academy of Agricultural Sciences, Hefei, 230031, China.<br /><searchLink fieldCode="AU" term="%22Xu+RH%22">Xu RH</searchLink>; Key Laboratory of Animal Genetics and Breeding of Zhejiang Province, Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Taian, 271001, China.<br /><searchLink fieldCode="AU" term="%22Fang+LZ%22">Fang LZ</searchLink>; Center for Quantitative Genetics and Genomics, Aarhus for University, Aarhus, 8000, Denmark. lingzhao.fang@qgg.au.dk.<br /><searchLink fieldCode="AU" term="%22Ding+XD%22">Ding XD</searchLink>; State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. xding@cau.edu.cn.; Frontier Technology Research Institute of China Agricultural University in Shenzhen, Shenzhen, 518119, China. xding@cau.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100965258 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2164 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712164%22">14712164 </searchLink><i>NLM ISO Abbreviation: </i>BMC Genomics <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12864-026-13117-8
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        Text: English
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              Text: 2026 Jul 10
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