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Genome-wide association and polygenic risk score analyses of MASLD-related hepatic steatosis severity in a Taiwanese Han population.

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Title: Genome-wide association and polygenic risk score analyses of MASLD-related hepatic steatosis severity in a Taiwanese Han population.
Authors: Liu TY; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan.; Master Program for Digital Health Innovation, China Medical University, Taichung, 406040, Taiwan., Yang JS; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan.; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan., Chen YC; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan.; Master Program for Digital Health Innovation, China Medical University, Taichung, 406040, Taiwan., Tsai SC; Department of Biological Science and Technology, China Medical University, Taichung, 406040, Taiwan., Chiu YJ; Department of Surgery, Division of Plastic and Reconstructive Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.; Department of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan., Liao CC; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan., Chang YT; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan., Shyu WC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung, 40402, Taiwan.; Department of Neurology, China Medical University Hospital, Taichung, 40402, Taiwan.; Neuroscience and Brain Disease Center, China Medical University, Taichung, 406040, Taiwan., Jeng LB; Cell Therapy Center, China Medical University Hospital, Taichung, 40402, Taiwan.; Organ Transplantation Center, China Medical University Hospital, Taichung, 40402, Taiwan., Tsai FJ; AI-Driven Genomic Medicine and Drug Discovery Lab, China Medical University Hospital, Taichung, 40402, Taiwan. 000704@tool.caaumed.org.tw.; School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan. 000704@tool.caaumed.org.tw.; Division of Pediatric Genetics, Children's Hospital of China Medical University, Taichung, 40447, Taiwan. 000704@tool.caaumed.org.tw.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, 41354, Taiwan. 000704@tool.caaumed.org.tw.
Source: Cell & bioscience [Cell Biosci] 2026 Jul 10. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101561195 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2045-3701 (Print) Linking ISSN: 20453701 NLM ISO Abbreviation: Cell Biosci
Database: MEDLINE Ultimate
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  Data: Genome-wide association and polygenic risk score analyses of MASLD-related hepatic steatosis severity in a Taiwanese Han population.
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  Data: <searchLink fieldCode="AU" term="%22Liu+TY%22">Liu TY</searchLink>; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan.; Master Program for Digital Health Innovation, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+JS%22">Yang JS</searchLink>; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan.; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan.; Master Program for Digital Health Innovation, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+SC%22">Tsai SC</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+YJ%22">Chiu YJ</searchLink>; Department of Surgery, Division of Plastic and Reconstructive Surgery, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.; Department of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+CC%22">Liao CC</searchLink>; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+YT%22">Chang YT</searchLink>; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, 40402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shyu+WC%22">Shyu WC</searchLink>; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung, 40402, Taiwan.; Department of Neurology, China Medical University Hospital, Taichung, 40402, Taiwan.; Neuroscience and Brain Disease Center, China Medical University, Taichung, 406040, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jeng+LB%22">Jeng LB</searchLink>; Cell Therapy Center, China Medical University Hospital, Taichung, 40402, Taiwan.; Organ Transplantation Center, China Medical University Hospital, Taichung, 40402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+FJ%22">Tsai FJ</searchLink>; AI-Driven Genomic Medicine and Drug Discovery Lab, China Medical University Hospital, Taichung, 40402, Taiwan. 000704@tool.caaumed.org.tw.; School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan. 000704@tool.caaumed.org.tw.; Division of Pediatric Genetics, Children's Hospital of China Medical University, Taichung, 40447, Taiwan. 000704@tool.caaumed.org.tw.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, 41354, Taiwan. 000704@tool.caaumed.org.tw.
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  Data: <searchLink fieldCode="JN" term="%22101561195%22">Cell & bioscience</searchLink> [Cell Biosci] 2026 Jul 10. <i>Date of Electronic Publication: </i>2026 Jul 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101561195 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2045-3701 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220453701%22">20453701 </searchLink><i>NLM ISO Abbreviation: </i>Cell Biosci
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        Value: 10.1186/s13578-026-01619-7
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        Text: English
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      – TitleFull: Genome-wide association and polygenic risk score analyses of MASLD-related hepatic steatosis severity in a Taiwanese Han population.
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            – D: 10
              M: 07
              Text: 2026 Jul 10
              Type: published
              Y: 2026
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