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Real-world treatment patterns and determinants of therapy in systemic sclerosis: findings from the German Network for SSc cohort.

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Title: Real-world treatment patterns and determinants of therapy in systemic sclerosis: findings from the German Network for SSc cohort.
Authors: Filla T; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Micu A; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Hansen L; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Grinberg I; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Deicher FS; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Lahu LM; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Matei AE; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Düsing C; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany., Riemekasten G; Clinic for Rheumatology and Clinical Immunology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany., Blank N; Division of Rheumatology, Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany., Alberding A; Department of Internal Medicine II- Internal Rheumatolgy, St. Josef Hospital Wuppertal, Wuppertal, Germany., Schmalzing M; Rheumatology/Clinical Immunology, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany., Ehrchen J; Department of Dermatology, University Hospital Münster, Münster, Germany., Günther C; Department of Dermatology, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany., Zeidler G; Department of Rheumatology, Osteology and Pain Therapy, Center for Rheumatology Brandenburg, Johanniter-Hospital Treuenbrietzen, Treuenbrietzen, Germany., Jandova I; Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, Germany., Keyßer G; Department of Internal Medicine, Division of Rheumatology, University Hospital Halle (Saale), Halle, Germany., Worm M; Department of Dermatology, Venereology and Allergology, Charité - Universitaetsmedizin Berlin, Berlin, Germany., Müller-Ladner U; Department of Rheumatology and Clinical Immunology, Justus-Liebig University Giessen, Kerckhoff Clinic, Bad Nauheim, Germany., Juche A; Department of Rheumatology, Immanuel Hospital Berlin-Buch, Berlin, Germany., Susok L; Department of Dermatology, Clinic Dortmund, Dortmund, Germany., Korsten P; Department of Rheumatology and Clinical Immunology, St. Josef-Stift Sendenhorst, Sendenhorst, Germany., Henes J; Centre for Interdisciplinary Rheumatology, Auto-inflammatory Diseases and Internal Medicine 2, University Hospital Tübingen, Tübingen, Germany., Kreuter A; Department of Dermatology, Venereology and Allergology, Helios St Elisabeth Hospital Oberhausen, University Witten/Herdecke, Oberhausen, Germany., Moinzadeh P; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany., Krieg T; Translational Matrix Biology, Faculty of Medicine, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany., Girke M; Center of Excellence Real World Evidence, Boehringer Ingelheim Pharma GmbH & Co.KG, Ingelheim am Rhein, Ingelheim am Rhein, Germany., Alves M; Therapeutic Area Inflammation, Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Ingelheim am Rhein, Germany., Hunzelmann N; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany., Distler JHW; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany. joerg.distler@med.uni-duesseldorf.de.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. joerg.distler@med.uni-duesseldorf.de.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany. joerg.distler@med.uni-duesseldorf.de., Györfi AH; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.
Source: Arthritis research & therapy [Arthritis Res Ther] 2026 Jul 10; Vol. 28 (1). Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world treatment patterns and determinants of therapy in systemic sclerosis: findings from the German Network for SSc cohort.
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  Data: <searchLink fieldCode="AU" term="%22Filla+T%22">Filla T</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Micu+A%22">Micu A</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Hansen+L%22">Hansen L</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Grinberg+I%22">Grinberg I</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Deicher+FS%22">Deicher FS</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Lahu+LM%22">Lahu LM</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Matei+AE%22">Matei AE</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Düsing+C%22">Düsing C</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Riemekasten+G%22">Riemekasten G</searchLink>; Clinic for Rheumatology and Clinical Immunology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Blank+N%22">Blank N</searchLink>; Division of Rheumatology, Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Alberding+A%22">Alberding A</searchLink>; Department of Internal Medicine II- Internal Rheumatolgy, St. Josef Hospital Wuppertal, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Schmalzing+M%22">Schmalzing M</searchLink>; Rheumatology/Clinical Immunology, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ehrchen+J%22">Ehrchen J</searchLink>; Department of Dermatology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+C%22">Günther C</searchLink>; Department of Dermatology, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Zeidler+G%22">Zeidler G</searchLink>; Department of Rheumatology, Osteology and Pain Therapy, Center for Rheumatology Brandenburg, Johanniter-Hospital Treuenbrietzen, Treuenbrietzen, Germany.<br /><searchLink fieldCode="AU" term="%22Jandova+I%22">Jandova I</searchLink>; Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Keyßer+G%22">Keyßer G</searchLink>; Department of Internal Medicine, Division of Rheumatology, University Hospital Halle (Saale), Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Worm+M%22">Worm M</searchLink>; Department of Dermatology, Venereology and Allergology, Charité - Universitaetsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Ladner+U%22">Müller-Ladner U</searchLink>; Department of Rheumatology and Clinical Immunology, Justus-Liebig University Giessen, Kerckhoff Clinic, Bad Nauheim, Germany.<br /><searchLink fieldCode="AU" term="%22Juche+A%22">Juche A</searchLink>; Department of Rheumatology, Immanuel Hospital Berlin-Buch, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Susok+L%22">Susok L</searchLink>; Department of Dermatology, Clinic Dortmund, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Korsten+P%22">Korsten P</searchLink>; Department of Rheumatology and Clinical Immunology, St. Josef-Stift Sendenhorst, Sendenhorst, Germany.<br /><searchLink fieldCode="AU" term="%22Henes+J%22">Henes J</searchLink>; Centre for Interdisciplinary Rheumatology, Auto-inflammatory Diseases and Internal Medicine 2, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kreuter+A%22">Kreuter A</searchLink>; Department of Dermatology, Venereology and Allergology, Helios St Elisabeth Hospital Oberhausen, University Witten/Herdecke, Oberhausen, Germany.<br /><searchLink fieldCode="AU" term="%22Moinzadeh+P%22">Moinzadeh P</searchLink>; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Krieg+T%22">Krieg T</searchLink>; Translational Matrix Biology, Faculty of Medicine, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Girke+M%22">Girke M</searchLink>; Center of Excellence Real World Evidence, Boehringer Ingelheim Pharma GmbH & Co.KG, Ingelheim am Rhein, Ingelheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Alves+M%22">Alves M</searchLink>; Therapeutic Area Inflammation, Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Ingelheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Hunzelmann+N%22">Hunzelmann N</searchLink>; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Distler+JHW%22">Distler JHW</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany. joerg.distler@med.uni-duesseldorf.de.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. joerg.distler@med.uni-duesseldorf.de.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany. joerg.distler@med.uni-duesseldorf.de.<br /><searchLink fieldCode="AU" term="%22Györfi+AH%22">Györfi AH</searchLink>; Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University, Düsseldorf, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.; Hiller Research Center, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, and Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, Germany. andrea-hermina.gyoerfi@med.uni-duesseldorf.de.
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