Age, Multidomain Lifestyle Intervention, and White Matter Integrity: Secondary Analysis of the POINTER Randomized Clinical Trial.

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Title: Age, Multidomain Lifestyle Intervention, and White Matter Integrity: Secondary Analysis of the POINTER Randomized Clinical Trial.
Authors: Maillard P; Department of Neurology, University of California, Davis., Vemuri P; Department of Radiology, Mayo Clinic, Rochester, Minnesota., Harvey DJ; Department of Neurology, University of California, Davis., Harrison TM; Helen Wills Neuroscience Institute, University of California, Berkeley., Reddy AL; Department of Radiology, Mayo Clinic, Rochester, Minnesota., Oh H; Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island.; Department of Cognitive and Psychological Sciences, Brown University, Providence, Rhode Island., Salloway S; Memory and Aging Program, Butler Hospital and Warren Alpert Medical School, Brown University, Providence, Rhode Island., Mahinrad S; Alzheimer's Association, Chicago, Illinois., Holland TM; Warren Alpert Medical School, Rush University, Chicago, Illinois., Whitmer R; Department of Neurology, University of California, Davis., Espeland MA; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina., Baker LD; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina., Landau SM; Helen Wills Neuroscience Institute, University of California, Berkeley., DeCarli C; Department of Neurology, University of California, Davis.
Source: JAMA network open [JAMA Netw Open] 2026 Jul 01; Vol. 9 (7), pp. e2620353. Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Age, Multidomain Lifestyle Intervention, and White Matter Integrity: Secondary Analysis of the POINTER Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Maillard+P%22">Maillard P</searchLink>; Department of Neurology, University of California, Davis.<br /><searchLink fieldCode="AU" term="%22Vemuri+P%22">Vemuri P</searchLink>; Department of Radiology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Harvey+DJ%22">Harvey DJ</searchLink>; Department of Neurology, University of California, Davis.<br /><searchLink fieldCode="AU" term="%22Harrison+TM%22">Harrison TM</searchLink>; Helen Wills Neuroscience Institute, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Reddy+AL%22">Reddy AL</searchLink>; Department of Radiology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Oh+H%22">Oh H</searchLink>; Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island.; Department of Cognitive and Psychological Sciences, Brown University, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22Salloway+S%22">Salloway S</searchLink>; Memory and Aging Program, Butler Hospital and Warren Alpert Medical School, Brown University, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22Mahinrad+S%22">Mahinrad S</searchLink>; Alzheimer's Association, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Holland+TM%22">Holland TM</searchLink>; Warren Alpert Medical School, Rush University, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Whitmer+R%22">Whitmer R</searchLink>; Department of Neurology, University of California, Davis.<br /><searchLink fieldCode="AU" term="%22Espeland+MA%22">Espeland MA</searchLink>; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Baker+LD%22">Baker LD</searchLink>; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Landau+SM%22">Landau SM</searchLink>; Helen Wills Neuroscience Institute, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22DeCarli+C%22">DeCarli C</searchLink>; Department of Neurology, University of California, Davis.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101729235 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2574-3805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225743805%22">25743805 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Netw Open <i>Subsets: </i>MEDLINE
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