Therapeutic Efficacy of Indole-3-Carbinol Against SARS-CoV-2-Induced Acute Respiratory Distress Syndrome: A Dual Antiviral and Anti-Inflammatory Approach in a Golden Syrian Hamster Model.

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Title: Therapeutic Efficacy of Indole-3-Carbinol Against SARS-CoV-2-Induced Acute Respiratory Distress Syndrome: A Dual Antiviral and Anti-Inflammatory Approach in a Golden Syrian Hamster Model.
Authors: Federica C; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy., Barbara R; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Andrea L; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.; UniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy., Michela B; Department of Biology, Tor Vergata University of Rome, Rome, Italy., Marco P; Anatomy and Pathological Histology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Francesca S; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy., Manuel S; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy., Alessandro M; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy., Palyi B; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary., Deri D; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium., Novak B; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary., Kis Z; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium., Filippone C; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium.; ERINHA Central Coordinating Unit, Paris cedex 13, France., Pandolfi PP; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Giuseppe N; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2026 Jul; Vol. 30 (13), pp. e71213.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Therapeutic Efficacy of Indole-3-Carbinol Against SARS-CoV-2-Induced Acute Respiratory Distress Syndrome: A Dual Antiviral and Anti-Inflammatory Approach in a Golden Syrian Hamster Model.
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  Data: <searchLink fieldCode="AU" term="%22Federica+C%22">Federica C</searchLink>; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Barbara+R%22">Barbara R</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Andrea+L%22">Andrea L</searchLink>; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.; UniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Michela+B%22">Michela B</searchLink>; Department of Biology, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Marco+P%22">Marco P</searchLink>; Anatomy and Pathological Histology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Francesca+S%22">Francesca S</searchLink>; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Manuel+S%22">Manuel S</searchLink>; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Alessandro+M%22">Alessandro M</searchLink>; Department of Experimental Medicine, and, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Palyi+B%22">Palyi B</searchLink>; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Deri+D%22">Deri D</searchLink>; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Novak+B%22">Novak B</searchLink>; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Kis+Z%22">Kis Z</searchLink>; National Center for Public Health and Pharmacy, National Biosafety Laboratory, Budapest, Hungary.; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Filippone+C%22">Filippone C</searchLink>; European Research Infrastructure on Highly Pathogenic Agents, ERINHA AISBL, Brussels, Belgium.; ERINHA Central Coordinating Unit, Paris cedex 13, France.<br /><searchLink fieldCode="AU" term="%22Pandolfi+PP%22">Pandolfi PP</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Giuseppe+N%22">Giuseppe N</searchLink>; Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
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        Value: 10.1111/jcmm.71213
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              Text: 2026 Jul
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