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Synergistic integration of μ-SPE and ammoniated adduct-based MRM for sensitive UPLC-MS/MS quantification of PEG1000: a comparative study against in-source CID and application to zebrafish tissue distribution.

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Title: Synergistic integration of μ-SPE and ammoniated adduct-based MRM for sensitive UPLC-MS/MS quantification of PEG1000: a comparative study against in-source CID and application to zebrafish tissue distribution.
Authors: Zhou X; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Duan S; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Lou Y; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Deng Y; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Feng S; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Liu J; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Zhang J; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Xi Y; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China., Shi M; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. shimy@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. shimy@dlut.edu.cn., Yin L; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. leiyin@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. leiyin@dlut.edu.cn.
Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-2650
DOI:10.1007/s00216-026-06654-4