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Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes.

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Title: Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes.
Authors: Gurung RL; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.; Cardiovascular and Metabolic Disorders Signature Research Program, Duke-NUS Medical School, Singapore, Singapore., Wu H; Genome Institute of Singapore, A*STAR, Singapore, Singapore., Zheng H; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore., Liu S; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore., Le Ivan Tan J; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore., Liu JJ; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore., Tay JH; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Academy for Healthy Longevity, National University of Singapore, Singapore, Singapore., Sim KS; Genome Institute of Singapore, A*STAR, Singapore, Singapore., Liu JJ; Genome Institute of Singapore, A*STAR, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Dorajoo R; Genome Institute of Singapore, A*STAR, Singapore, Singapore. dorajoor@a-star.edu.sg.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. dorajoor@a-star.edu.sg., Lim SC; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore. lim.su.chi@nhghealth.com.sg.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. lim.su.chi@nhghealth.com.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. lim.su.chi@nhghealth.com.sg.
Source: GeroScience [Geroscience] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Gurung+RL%22">Gurung RL</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.; Cardiovascular and Metabolic Disorders Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Genome Institute of Singapore, A*STAR, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.<br /><searchLink fieldCode="AU" term="%22Le+Ivan+Tan+J%22">Le Ivan Tan J</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+JJ%22">Liu JJ</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore.<br /><searchLink fieldCode="AU" term="%22Tay+JH%22">Tay JH</searchLink>; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Academy for Healthy Longevity, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sim+KS%22">Sim KS</searchLink>; Genome Institute of Singapore, A*STAR, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+JJ%22">Liu JJ</searchLink>; Genome Institute of Singapore, A*STAR, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Dorajoo+R%22">Dorajoo R</searchLink>; Genome Institute of Singapore, A*STAR, Singapore, Singapore. dorajoor@a-star.edu.sg.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. dorajoor@a-star.edu.sg.<br /><searchLink fieldCode="AU" term="%22Lim+SC%22">Lim SC</searchLink>; Clinical Research Unit, Khoo Teck Puat Hospital, Yishun, Singapore. lim.su.chi@nhghealth.com.sg.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. lim.su.chi@nhghealth.com.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. lim.su.chi@nhghealth.com.sg.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2026 Jul 13. <i>Date of Electronic Publication: </i>2026 Jul 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11357-026-02396-4
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        Text: English
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            – D: 13
              M: 07
              Text: 2026 Jul 13
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              Y: 2026
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