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Integrated miRNA-mRNA network analysis identifies miR-182-5p as a potential regulator in COPD pathogenesis.

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Title: Integrated miRNA-mRNA network analysis identifies miR-182-5p as a potential regulator in COPD pathogenesis.
Authors: Burke H; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Ackland J; Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Angermann BR; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Belfield G; Translational Genomics, Centre for Genomics Research, Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Cellura D; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Etal D; Translational Genomics, Centre for Genomics Research, Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Humbert MV; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Freeman A; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Rydin L; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ostridge K; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; Early Clinical Development, Respiratory and Immunology R&D Biopharmaceuticals, AstraZeneca, Gothenburg, Sweden., Platt A; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, Biopharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Watson A; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Spalluto CM; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Staples KJ; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom., Wilkinson TMA; Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom.
Source: Frontiers in medicine [Front Med (Lausanne)] 2026 Jun 22; Vol. 13, pp. 1743277. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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