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Ablating Satb1 reprograms the differentiation trajectory of exhausted CD8+ T subsets to enhance antitumor immunity.

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Title: Ablating Satb1 reprograms the differentiation trajectory of exhausted CD8+ T subsets to enhance antitumor immunity.
Authors: Wu L; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China., Jiang H; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China., Gao J; Department of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China., Ji X; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Chen Y; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China., Ma Z; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China., Li X; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China., Wang J; Department of General Surgery, The Fourth Affiliated Hospital of Soochow University, (Suzhou Dushu Lake Hospital), Suzhou, China., Zang Y; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Zhang J; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Zhao X; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China., Wang X; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 22; Vol. 17, pp. 1744549. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ablating Satb1 reprograms the differentiation trajectory of exhausted CD8<superscript>+</superscript> T subsets to enhance antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Department of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Ji+X%22">Ji X</searchLink>; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Ma+Z%22">Ma Z</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of General Surgery, The Fourth Affiliated Hospital of Soochow University, (Suzhou Dushu Lake Hospital), Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zang+Y%22">Zang Y</searchLink>; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; The First Affiliated Hospital of Soochow University and The Second Affiliated Hospital of Soochow University and The Fourth Affiliated Hospital of Soochow University and School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1744549
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              Text: 2026 Jun 22
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